| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10002345m |
| Family | GT47 |
| Protein Properties | Length: 464 Molecular Weight: 53355 Isoelectric Point: 9.117 |
| Chromosome | Chromosome/Scaffold: 32 Start: 13075 End: 16912 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 128 | 414 | 0 |
| KRFKVWSYKEGEQPLVHDGPVNDIYGIEGQFIDELGNVMGGRFSAGQPEEAHAFFLPFSVANIVHYVYKPITSSADFNRDRLHRIFNDYVDVVARKYPFW NQSNGADHFMVSCHDWAPEVSDSKPEFFKDFIRGLCNANTSEGFRPNIDFSIPEINIPKGKLKPPFMGQPPENRTILAFFAGRAHGYIREVLFNHWKGND RDIQVYDGLTKGQNYHELIGHSKFCLCPSGYEVASPREVEAIYSGCVPVVISNNYSLPFSDVLDWSKFSVEIPIDKISEIKRILQKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 464 Download |
| MPNDSSKTYC LLRFPLVLLL LFLVFSSFPN TGSPPQHFFS IALSPPFHHT NALQSSSPSS 60 SLYSPPIPIT KRSNLEKREE ELRKARTAIR RAVKFKNYTS NEDVTYIPTG QIYRNSFAFY 120 QSHTEMMKRF KVWSYKEGEQ PLVHDGPVND IYGIEGQFID ELGNVMGGRF SAGQPEEAHA 180 FFLPFSVANI VHYVYKPITS SADFNRDRLH RIFNDYVDVV ARKYPFWNQS NGADHFMVSC 240 HDWAPEVSDS KPEFFKDFIR GLCNANTSEG FRPNIDFSIP EINIPKGKLK PPFMGQPPEN 300 RTILAFFAGR AHGYIREVLF NHWKGNDRDI QVYDGLTKGQ NYHELIGHSK FCLCPSGYEV 360 ASPREVEAIY SGCVPVVISN NYSLPFSDVL DWSKFSVEIP IDKISEIKRI LQKIPHDKYL 420 RMYKNVMKVK RHFVVNRPAQ PFDVIHMILH SVWLRRLNIQ LPS* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-62 | 126 | 414 | 308 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABA18091.1 | 0 | 126 | 463 | 1 | 341 | exostosin family protein [Olimarabidopsis pumila] |
| GenBank | ABA18105.1 | 0 | 43 | 463 | 1 | 423 | exostosin family protein [Capsella rubella] |
| GenBank | ABA18110.1 | 0 | 127 | 463 | 1 | 340 | exostosin family protein [Arabidopsis arenosa] |
| GenBank | ABG48476.1 | 0 | 49 | 463 | 7 | 425 | At3g42180 [Arabidopsis thaliana] |
| RefSeq | NP_189804.4 | 0 | 30 | 463 | 32 | 470 | catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
