| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10002514m |
| Family | GT47 |
| Protein Properties | Length: 472 Molecular Weight: 54414.2 Isoelectric Point: 8.9868 |
| Chromosome | Chromosome/Scaffold: 4 Start: 10214033 End: 10215776 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 76 | 394 | 0 |
| KEPLKVYMYDMDPEFHFGLLDWKPEKKNSVWPDIQKYIPPYPGGLNLQHSIEYWLTLDILASEYPNAPRAIAAKRVHNSTEADVIFVPFFSSLSYNRFSK VNPHQKTSRNKDLQGKLVAFLTTQEEWKRSGGRDHVVLAHHPNSMLDARNKLFPAMFILSDFGRYPPTVANVEKDIIAPYKHVIKGYENDTSGFDTRPIL LYFQGAIYRKDGGFVRQELFYLLQDEKDVHFSFGSVRNGGVNKASQGMHNSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDDIELPFEDVIDYSEFSVF VRTSDALKENFLVNLIRGI | |||
| Full Sequence |
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| Protein Sequence Length: 472 Download |
| MAMVEKNGST IGYVARNLLL CLFLVTTILF ALSCYFVLRS TAHNRFLSST FPSKSFLDDV 60 NVKEAKQEKE NCRCSKEPLK VYMYDMDPEF HFGLLDWKPE KKNSVWPDIQ KYIPPYPGGL 120 NLQHSIEYWL TLDILASEYP NAPRAIAAKR VHNSTEADVI FVPFFSSLSY NRFSKVNPHQ 180 KTSRNKDLQG KLVAFLTTQE EWKRSGGRDH VVLAHHPNSM LDARNKLFPA MFILSDFGRY 240 PPTVANVEKD IIAPYKHVIK GYENDTSGFD TRPILLYFQG AIYRKDGGFV RQELFYLLQD 300 EKDVHFSFGS VRNGGVNKAS QGMHNSKFCL NIAGDTPSSN RLFDAIASHC VPVIISDDIE 360 LPFEDVIDYS EFSVFVRTSD ALKENFLVNL IRGITKEEWT RMWNRLKEVE KFYEFHFPSK 420 VDDAVQMIWQ AIARKVPGVK MRIHKSRRYS KSVSETERES RWSSLIPRSF W* 480 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-57 | 75 | 394 | 330 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_190126.1 | 0 | 1 | 471 | 1 | 475 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002268382.1 | 0 | 3 | 471 | 1 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002319201.1 | 0 | 1 | 450 | 1 | 450 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002325457.1 | 0 | 3 | 471 | 1 | 463 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002530948.1 | 0 | 62 | 461 | 84 | 491 | catalytic, putative [Ricinus communis] |
