| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10003789m |
| Family | GT47 |
| Protein Properties | Length: 653 Molecular Weight: 73690.8 Isoelectric Point: 9.7917 |
| Chromosome | Chromosome/Scaffold: 6 Start: 3728861 End: 3732023 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 319 | 604 | 0 |
| EKMLKVYVYKEGDRPIMHSPMLRGIYASEGWFMKLIESNNNKFVTKDPSKAHLFYLPFSSRMLEVTLYVQDSHSHRNLIQYLKDYIDFISVKYPFWNRTS GADHFLAACHDWAPSETRKHFSKSIRALCNSDVKEGFVFGKDTSLPETFVRDPKKPLSSLGGKSASQRPILAFFAGKPEHGYLRPILLSYWGNNKDPDLK IFGKLPRTKGNKNYLQFMKTSKYCICAKGYEVNSPRVVEAIFYDCVPVIISDNFVPPFFEVLNWESFALFVPEKDIPNLKKILMSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 653 Download |
| MRHELPWLWK VESRRLLWLL GLTFALIVTF QYIELPYAIS SLFSSTKIPF SRNSTSLLGD 60 GEHHNGNLTP AMAPSFSQKN STLTNSEGDE EEVEVDQIFD SRGNATAPSA LPNATAHNAR 120 AEAPVSLPGF TPSSVKENAT AHNAEAPADA LPGLNPSPVK ENATAPAAYA EAPAVSPGLK 180 KNATTPVASV EAPALLPGLS PSPVKENATT SQVPKKNPTK KAVGDASPVV RFVPDLKENG 240 KMPDSGVMSI SEMSKKLREN RISHNRLAKK PKWVTKPDLE LLQARYEIEN APIDDKDPLL 300 YAPLYRNVSI FKRSYELMEK MLKVYVYKEG DRPIMHSPML RGIYASEGWF MKLIESNNNK 360 FVTKDPSKAH LFYLPFSSRM LEVTLYVQDS HSHRNLIQYL KDYIDFISVK YPFWNRTSGA 420 DHFLAACHDW APSETRKHFS KSIRALCNSD VKEGFVFGKD TSLPETFVRD PKKPLSSLGG 480 KSASQRPILA FFAGKPEHGY LRPILLSYWG NNKDPDLKIF GKLPRTKGNK NYLQFMKTSK 540 YCICAKGYEV NSPRVVEAIF YDCVPVIISD NFVPPFFEVL NWESFALFVP EKDIPNLKKI 600 LMSISERRYK QMQMRVKKVQ KHFLWHVKPE KFDMFHMILH SVWFNRVFQV SV* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-65 | 318 | 604 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_195005.1 | 0 | 235 | 650 | 182 | 593 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_197954.1 | 0 | 1 | 652 | 1 | 654 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002281263.1 | 0 | 1 | 652 | 1 | 668 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002309547.1 | 0 | 202 | 651 | 26 | 469 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002324801.1 | 0 | 267 | 650 | 13 | 395 | predicted protein [Populus trichocarpa] |
