| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10005794m |
| Family | GT47 |
| Protein Properties | Length: 792 Molecular Weight: 90598.1 Isoelectric Point: 6.3678 |
| Chromosome | Chromosome/Scaffold: 19 Start: 2067858 End: 2072429 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 343 | 696 | 0 |
| KKRPLIYIYDLPPDFNSLLLEGRHFKLECVNRIYDDRNATIWTDYLYGSQMAFYENILATAHRTLNGEEADFFFVPVLDSCIITRADDAPHLSMQNHTGL RSSLTLEFYKRAYEHIVEKYPYWNRSSGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNSKHNHSTTAYWGDNWDEISNERRGDHPCFDPRKDLVIPA WKVPDPFSMRANYWARPREKRKTLFYFNGNLGPAYEKGRPEDSYSMGIRQKLAEEFGSSPNKEGKLGKQHADDVVVTPLRSDNYHNDIATSIFCGVFPGD GWSGRMEDSILQGCVPVIIQDGIYLPYENMLNYESFAVRVSEDDIPSLINTLRG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 792 Download |
| MFSHQKWKCS WSQIATVASV IVLVSLVHIF LGPVVPSFDS VSVRQAQNLS GTSNDSIRQV 60 SEDSSKTVVA FDRRFPADLH GAVVYRNASW KAEIGQWLSS CDAVAKDVDI IEPIGGRKCL 120 NDCSSQGVCN HEFGICRCFH GYTGEDCSQK LRLECNYEKT PEMPYGRWVV SICSRHCDTT 180 RAMCFCGEGT KYPNRPVPES CGFQINSPVN PDEPKMTDWS KPDLDILTTN SSKQGWCNVD 240 PEDAYALKVQ IKEECDCKYD CLWGRFCEVP VQCTCVNQCS GHGKCRGGFC QCDKGWFGTD 300 CSIPSTLSTV GEWPQWLRPA HLEVPSDKNV PGNLSNISAV VKKKRPLIYI YDLPPDFNSL 360 LLEGRHFKLE CVNRIYDDRN ATIWTDYLYG SQMAFYENIL ATAHRTLNGE EADFFFVPVL 420 DSCIITRADD APHLSMQNHT GLRSSLTLEF YKRAYEHIVE KYPYWNRSSG RDHIWFFSWD 480 EGACYAPKEI WNSMMLVHWG NTNSKHNHST TAYWGDNWDE ISNERRGDHP CFDPRKDLVI 540 PAWKVPDPFS MRANYWARPR EKRKTLFYFN GNLGPAYEKG RPEDSYSMGI RQKLAEEFGS 600 SPNKEGKLGK QHADDVVVTP LRSDNYHNDI ATSIFCGVFP GDGWSGRMED SILQGCVPVI 660 IQDGIYLPYE NMLNYESFAV RVSEDDIPSL INTLRGFNET EIQFRLANVK KIWQRFLFRD 720 SILLEAERQK ASFGHEEDWA VQFSKLKHDD IFATFIQTLH FKLHNDPWRR EQVVNRTKEY 780 GLPQECLQKT S* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 9.0e-5 | 273 | 301 | 31 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 9.0e-67 | 342 | 697 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005515 | protein binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAB41192.1 | 0 | 1 | 791 | 1 | 736 | putative protein [Arabidopsis thaliana] |
| EMBL | CBI29877.1 | 0 | 2 | 790 | 31 | 821 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_191322.3 | 0 | 1 | 791 | 1 | 793 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_974452.1 | 0 | 1 | 791 | 1 | 791 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002277596.1 | 0 | 2 | 790 | 3 | 793 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3a7q_A | 0.002 | 275 | 347 | 537 | 608 | B Chain B, Structural Basis For Specific Recognition Of Reelin By Its Receptors |
| PDB | 2e26_A | 0.002 | 275 | 347 | 537 | 608 | A Chain A, Crystal Structure Of Two Repeat Fragment Of Reelin |
