Basic Information | |
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Species | Thellungiella halophila |
Cazyme ID | Thhalv10006713m |
Family | CBM43 |
Protein Properties | Length: 950 Molecular Weight: 104463 Isoelectric Point: 6.9285 |
Chromosome | Chromosome/Scaffold: 5 Start: 11584573 End: 11589634 |
Description | O-Glycosyl hydrolases family 17 protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
CBM43 | 387 | 468 | 5.4e-34 |
CIAMDSVDAKTLQAALDWACGPGRANCSEIQPGESCYQPNNVKGHASFAFNNYYQKEGRASGSCDFKGVAMITTTDPSHGSC | |||
GH17 | 49 | 368 | 0 |
VGFNIGTDVSNLLTPAELVKFLQTQKINHVRLYDADPDLLNALAKTKIRVIISVPNNQLLAIGSSNSTAASWIGRNVVAYYPETLITAISVGDEVLTTVP SSAPLLLPAIESLYNALVASNLHTQIKVSTPHAASIMLDTFPPSQAYFNQTWHSVMVPLLQFLSKTGSPLMMNLYPYYVYMQNKGVVPLDNCLFEPLTPA KEMVDPNTLLHYTNVLDAMVDAAYVSMKNLNVSDVVVLVTESGWPWKGDSKEPHATIDNADTYNSNLIKHVFDRTGTPLHPEMTPSVYIYELFNEDKRAP PVSEASWGLFSGNSTPVYLL |
Full Sequence |
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Protein Sequence Length: 950 Download |
MALTSMVSTI PVFFSFFFLV ISNLLLISAN SSSLSQDIRI QEQDKDPFVG FNIGTDVSNL 60 LTPAELVKFL QTQKINHVRL YDADPDLLNA LAKTKIRVII SVPNNQLLAI GSSNSTAASW 120 IGRNVVAYYP ETLITAISVG DEVLTTVPSS APLLLPAIES LYNALVASNL HTQIKVSTPH 180 AASIMLDTFP PSQAYFNQTW HSVMVPLLQF LSKTGSPLMM NLYPYYVYMQ NKGVVPLDNC 240 LFEPLTPAKE MVDPNTLLHY TNVLDAMVDA AYVSMKNLNV SDVVVLVTES GWPWKGDSKE 300 PHATIDNADT YNSNLIKHVF DRTGTPLHPE MTPSVYIYEL FNEDKRAPPV SEASWGLFSG 360 NSTPVYLLHV SGSGTFLAND TTNQTYCIAM DSVDAKTLQA ALDWACGPGR ANCSEIQPGE 420 SCYQPNNVKG HASFAFNNYY QKEGRASGSC DFKGVAMITT TDPSHGSCIF PGSKKVGNRT 480 QTVVNSTQVA AGEASSRSLS RCFCVRQMST TRFLRLLTTL AMSSSSSSSS WSCNKCTFLN 540 SPSQKLKCMI CLTPVSVPSS ISISSNNEPK WACKGCTFLN SYKNSLCDIC GTRSPSSSLL 600 GFDELTDSGL ENNNNNNPDC SVGSVFFPLR RCSKRKAMDD DVIEVDGGSV ARSESLGLMK 660 KNKEIDTKGV ASESGTLISC LKILSYNVWF REDLELNLRM KAIGHLIQLH SPHLICFQEV 720 TPEIYVIFSK SNWWKAYSCS VSFDVAQSRA YFCMLLSKVG VKSFSCKSFR NSIMGRELSV 780 AEVEVPGRKP LVLATSHLES PCPGPPKWDQ MFSQERVEQA REAIEILGAN TNVIFGGDMN 840 WDDKLDGKFP LPDKWVDVWE VLKPGDSGFT YDTKANPMLS GNRTLQKRLD RILCRLDDYK 900 LGGIEMVGKE AIPGLSHVKE KKVRGEIKKL ELPVLPSDHF GLLLTLSPK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd08372 | EEP | 3.0e-10 | 683 | 946 | 284 | + Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily. This large superfamily includes the catalytic domain (exonuclease/endonuclease/phosphatase or EEP domain) of a diverse set of proteins including the ExoIII family of apurinic/apyrimidinic (AP) endonucleases, inositol polyphosphate 5-phosphatases (INPP5), neutral sphingomyelinases (nSMases), deadenylases (such as the vertebrate circadian-clock regulated nocturnin), bacterial cytolethal distending toxin B (CdtB), deoxyribonuclease 1 (DNase1), the endonuclease domain of the non-LTR retrotransposon LINE-1, and related domains. These diverse enzymes share a common catalytic mechanism of cleaving phosphodiester bonds; their substrates range from nucleic acids to phospholipids and perhaps proteins. | ||
pfam07983 | X8 | 6.0e-23 | 385 | 457 | 78 | + X8 domain. The X8 domain domain contains at least 6 conserved cysteine residues that presumably form three disulphide bridges. The domain is found in an Olive pollen allergen as well as at the C-terminus of several families of glycosyl hydrolases. This domain may be involved in carbohydrate binding. This domain is characteristic of GPI-anchored domains. | ||
smart00768 | X8 | 7.0e-42 | 385 | 470 | 86 | + Possibly involved in carbohydrate binding. The X8 domain, which may be involved in carbohydrate binding, is found in an Olive pollen antigen as well as at the C terminus of family 17 glycosyl hydrolases. It contains 6 conserved cysteine residues which presumably form three disulfide bridges. | ||
cd09080 | TDP2 | 6.0e-82 | 681 | 946 | 272 | + Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains. Human TDP2, also known as TTRAP (TRAF/TNFR-associated factors, and tumor necrosis factor receptor/TNFR-associated protein), is a 5'-tyrosyl DNA phosphodiesterase. It is required for the efficient repair of topoisomerase II-induced DNA double strand breaks. The topoisomerase is covalently linked by a phosphotyrosyl bond to the 5'-terminus of the break. TDP2 cleaves the DNA 5'-phosphodiester bond and restores 5'-phosphate termini, needed for subsequent DNA ligation, and hence repair of the break. TDP2 and 3'-tyrosyl DNA phosphodiesterase (TDP1) are complementary activities; together, they allow cells to remove trapped topoisomerase from both 3'- and 5'-DNA termini. TTRAP has been reported as being involved in apoptosis, embryonic development, and transcriptional regulation, and it may inhibit the activation of nuclear factor-kB. This family belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds. | ||
pfam00332 | Glyco_hydro_17 | 3.0e-82 | 49 | 366 | 318 | + Glycosyl hydrolases family 17. |
Gene Ontology | |
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GO Term | Description |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0005622 | intracellular |
GO:0005975 | carbohydrate metabolic process |
GO:0008270 | zinc ion binding |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC17632.1 | 0 | 1 | 464 | 1 | 459 | Similar to glucan endo-1,3-beta-D-glucosidase precursor gb |
EMBL | CBI23232.1 | 0 | 17 | 947 | 17 | 959 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002316541.1 | 0 | 61 | 500 | 1 | 440 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002332610.1 | 0 | 61 | 523 | 1 | 462 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518468.1 | 0 | 9 | 497 | 7 | 498 | Glucan endo-1,3-beta-glucosidase precursor, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2cyg_A | 0 | 49 | 366 | 1 | 308 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
PDB | 3ur8_B | 0 | 49 | 371 | 3 | 315 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
PDB | 3ur8_A | 0 | 49 | 371 | 3 | 315 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
PDB | 3ur7_B | 0 | 49 | 371 | 3 | 315 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |
PDB | 3ur7_A | 0 | 49 | 371 | 3 | 315 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |