| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10007515m |
| Family | GT47 |
| Protein Properties | Length: 479 Molecular Weight: 54496.4 Isoelectric Point: 8.7983 |
| Chromosome | Chromosome/Scaffold: 5 Start: 345841 End: 348191 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 55 | 402 | 0 |
| NGINVFVAELPRSLNYGLLEKYWSSSPDSRIPNDPDRPTRKTNLPKPDKYPPYPENPLIKQYSAEYWIMGDLETPPENRAGSFAKRVFSESDADVVFVPF FATLSAEMELGNGKGSFRKKSGNEDYQRQRQVLDFVKNTQAWKRSNGRDHVFVLTDPVAMWHVREEIALSILLVVDFGGWFRQDSKSSSGTSLPEKIEHT QVSVIKDVIVPYTHLLPRLDLSRNQRRHSLLYFKGAKHRHRGGLIREKLWDLLVDEDGVVMEEGFPNATGREQSIRGMRNSEFCLHPAGDTPTSCRLFDA IQSLCIPVIVSDTIELPFEGIIDYSEFSVFVSVSDALTPKWLANHLRR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 479 Download |
| MVPKITSMAV TRPLCSVSCL FLSFSLVFII PLLFFFSNFL ISDPNPRISH NTFQNGINVF 60 VAELPRSLNY GLLEKYWSSS PDSRIPNDPD RPTRKTNLPK PDKYPPYPEN PLIKQYSAEY 120 WIMGDLETPP ENRAGSFAKR VFSESDADVV FVPFFATLSA EMELGNGKGS FRKKSGNEDY 180 QRQRQVLDFV KNTQAWKRSN GRDHVFVLTD PVAMWHVREE IALSILLVVD FGGWFRQDSK 240 SSSGTSLPEK IEHTQVSVIK DVIVPYTHLL PRLDLSRNQR RHSLLYFKGA KHRHRGGLIR 300 EKLWDLLVDE DGVVMEEGFP NATGREQSIR GMRNSEFCLH PAGDTPTSCR LFDAIQSLCI 360 PVIVSDTIEL PFEGIIDYSE FSVFVSVSDA LTPKWLANHL RRFSERDKET FRSRMAKVQR 420 VFVYDNGQAD GIGPVQPDGA VNHIWKKVWE KVPMVKEAVI RERRKPAGAS VPLRCQCI* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-57 | 92 | 403 | 324 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564443.1 | 0 | 1 | 478 | 1 | 477 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002270238.1 | 0 | 1 | 477 | 1 | 439 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325567.1 | 0 | 15 | 477 | 13 | 475 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002327326.1 | 0 | 33 | 477 | 5 | 448 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002533317.1 | 0 | 41 | 477 | 39 | 477 | catalytic, putative [Ricinus communis] |
