| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10007584m |
| Family | GT47 |
| Protein Properties | Length: 461 Molecular Weight: 52490 Isoelectric Point: 9.5826 |
| Chromosome | Chromosome/Scaffold: 5 Start: 8015809 End: 8018368 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 85 | 383 | 0 |
| LSLKIYVYDENEIDGLKELMYGRDGSVKTTACLKGQWGSQVKIHKLLLESKFRTSKKDEADLFFVPAYVKCVRMLGGLNDKEINQTYVKVLSQMPYFRRS GGRDHIFVFPSGAGAHLFRSWSTFINRSIILTPEGDRTDKKDTTAFNTWKDIIIPGNVDDAMTKNGQPDVQPLPLSKRKYLANYLGRAQGKAGRLKLIDL SKQYPDKLECPDLKFSGTEKFGRTTYFEHLRNAKFCLAPRGESSWTLRFYESFFVECVPVLLSDHAELPFQNVIDYAQVSIKWPSTRIGAELLDYLASI | |||
| Full Sequence |
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| Protein Sequence Length: 461 Download |
| MASLTSKPRN FGAYSHYATP CTRTHQIGAL FLVVSTFFVT RLFDQWFSES NSVTPAIDLR 60 RTSSSGITDD NGIPRWPERG YGSHLSLKIY VYDENEIDGL KELMYGRDGS VKTTACLKGQ 120 WGSQVKIHKL LLESKFRTSK KDEADLFFVP AYVKCVRMLG GLNDKEINQT YVKVLSQMPY 180 FRRSGGRDHI FVFPSGAGAH LFRSWSTFIN RSIILTPEGD RTDKKDTTAF NTWKDIIIPG 240 NVDDAMTKNG QPDVQPLPLS KRKYLANYLG RAQGKAGRLK LIDLSKQYPD KLECPDLKFS 300 GTEKFGRTTY FEHLRNAKFC LAPRGESSWT LRFYESFFVE CVPVLLSDHA ELPFQNVIDY 360 AQVSIKWPST RIGAELLDYL ASIPDRDIEG MIGRGRKIRC LFVYGPDSAP CNAVKGILWE 420 LQRKVRHFHQ STETFWLHNG SFVNRELVHF SSWRPPMSLP * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-45 | 87 | 383 | 309 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF87908.1 | 0 | 1 | 460 | 1 | 414 | AC015447_18 Hypothetical protein [Arabidopsis thaliana] |
| GenBank | AAL75891.1 | 0 | 1 | 460 | 1 | 462 | At1g21480/F24J8_23 [Arabidopsis thaliana] |
| GenBank | AAM61682.1 | 0 | 1 | 460 | 1 | 462 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_564141.1 | 0 | 1 | 460 | 1 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_973879.1 | 0 | 1 | 383 | 1 | 385 | exostosin family protein [Arabidopsis thaliana] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| BX841155 | 335 | 1 | 333 | 0 |
| EX093096 | 286 | 1 | 285 | 0 |
| CX668832 | 291 | 147 | 437 | 0 |
| CD825121 | 244 | 155 | 398 | 0 |
| FE707914 | 279 | 127 | 405 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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