| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10007763m |
| Family | GT47 |
| Protein Properties | Length: 413 Molecular Weight: 46820.9 Isoelectric Point: 6.8976 |
| Chromosome | Chromosome/Scaffold: 5 Start: 5805825 End: 5807849 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 45 | 340 | 0 |
| RLKVYVYELPSKYNKKLLQKDPRCLTHMFAAEIFMHRFLLSSPVRTRNPEEADWFYTPIYPTCDLTPTGLPLPFKSPRMMRSAIQLISSNWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIERGILPLLQRATLVQTFGQRNHVCLDDGSITIPPFAPPQKMQAHLIPPDIPRSIFVYFRGLFYDVNNDPEGGYYARGA RAAVWENFKNNPLFDISTDHPTTYYEDMQRSIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVGEKDVPELDTILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 413 Download |
| MTNRSSLSAI LLFLFFSASS AEHNVRTERI SGSAGDVLED DPVGRLKVYV YELPSKYNKK 60 LLQKDPRCLT HMFAAEIFMH RFLLSSPVRT RNPEEADWFY TPIYPTCDLT PTGLPLPFKS 120 PRMMRSAIQL ISSNWPYWNR TEGADHFFVV PHDFGACFHY QEEKAIERGI LPLLQRATLV 180 QTFGQRNHVC LDDGSITIPP FAPPQKMQAH LIPPDIPRSI FVYFRGLFYD VNNDPEGGYY 240 ARGARAAVWE NFKNNPLFDI STDHPTTYYE DMQRSIFCLC PLGWAPWSPR LVEAVVFGCI 300 PVIIADDIVL PFADAIPWEE IGVFVGEKDV PELDTILTSI PTQVILRKQR LLANPSMKRA 360 MLFPQPAQPG DAFHQILNGL ARKLPHDRSI YLKAGEKVLN WTAGPVGDLK PW* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-82 | 45 | 340 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33320.1 | 0 | 7 | 412 | 8 | 412 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | NP_174064.1 | 0 | 1 | 412 | 1 | 412 | GUT2; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002297880.1 | 0 | 7 | 412 | 8 | 412 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002304637.1 | 0 | 18 | 412 | 19 | 413 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511079.1 | 0 | 9 | 412 | 10 | 417 | catalytic, putative [Ricinus communis] |
