| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10013011m |
| Family | GT47 |
| Protein Properties | Length: 607 Molecular Weight: 70076 Isoelectric Point: 10.0954 |
| Chromosome | Chromosome/Scaffold: 2 Start: 6778100 End: 6781147 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 275 | 557 | 0 |
| RMLKVYVYKEGNRPIFHTPILKGLYASEGWFMKLMEANKHYTVKDPRRAHLYYMPFSARMLEYTLYVRNSHNRTNLRQFLKEYTEQIGSKYPFFNRTGGA DHFLVACHDWAPYETRHHMEHCIKALCNADITAGFKIGRDISLPETYVRAAKNPLRDLGGKPPSQRRTLAFYAGSMHGYLRPILLQHWKDKDPEMKIFGR MPLGVASKMNYIEQMKNSKFCICPKGYEVNSPRVVESIFYECVPVIISDNFVPPFFEVLDWSMFSVIVAEKDIPRLKDILSSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 607 Download |
| MEIRSELRKF SRSGKRKWAI LVGILALTHI SLLLSYGRYL LPDGRRLKLP NENNTLMNPS 60 QNALLRNTLA VNVSEVPAGL EKNGYVTGSG PRNDSEDDEG FVDSVDFEGF EDAKDSVIIK 120 EVAVNSDSLF PSEKVVMKNE GLLTSNHGHQ EQNVSLQSQK NVKSSKLNAG NSIAAPVLGN 180 SSLPVSKQVG KKKKMRCDLP PKTVTTIDEM NRILARHRRS SRAMRPRWSS RRDEEILAAR 240 KEIENAPVVT IDRELYPPIF RNVSMFKRSY ELMERMLKVY VYKEGNRPIF HTPILKGLYA 300 SEGWFMKLME ANKHYTVKDP RRAHLYYMPF SARMLEYTLY VRNSHNRTNL RQFLKEYTEQ 360 IGSKYPFFNR TGGADHFLVA CHDWAPYETR HHMEHCIKAL CNADITAGFK IGRDISLPET 420 YVRAAKNPLR DLGGKPPSQR RTLAFYAGSM HGYLRPILLQ HWKDKDPEMK IFGRMPLGVA 480 SKMNYIEQMK NSKFCICPKG YEVNSPRVVE SIFYECVPVI ISDNFVPPFF EVLDWSMFSV 540 IVAEKDIPRL KDILSSIPEE KYVKMQMAVR KAQRHFLWHA KPERYDLFHM VLHSIWYNRV 600 FQAKRR* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-66 | 277 | 557 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN76867.1 | 0 | 205 | 602 | 264 | 709 | hypothetical protein [Vitis vinifera] |
| EMBL | CAN76867.1 | 0 | 224 | 603 | 1012 | 1391 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_197468.1 | 0 | 1 | 606 | 1 | 600 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002283936.1 | 0 | 199 | 606 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002514248.1 | 0 | 42 | 606 | 38 | 676 | catalytic, putative [Ricinus communis] |
