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Basic Information | |
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Species | Thellungiella halophila |
Cazyme ID | Thhalv10013187m |
Family | GT47 |
Protein Properties | Length: 544 Molecular Weight: 63001.4 Isoelectric Point: 9.8616 |
Chromosome | Chromosome/Scaffold: 2 Start: 3791957 End: 3793988 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 214 | 495 | 0 |
EKTLKVYVYSEGDRPIFHQPEAIMEGVYASEGWFMKLMESNSRFLTKDPTKAHLFYLAFNSRILQQKLYVRDSHRRRNLVKYLRDYINLIISKYPFWNRT RGSDHFFTACHDWAPAETRGPYMNCIRSLCNADVGVDFIVGKDVSLPETKVSSSQTPNGNIGGNRPSKRTILAFFAGNLHGYVRPILLNQWSSRPEPDMK IFNRIDHKSYIRFMKRSRFCVCAKGYEVNSPRVVESVLYGCVPVIISDNFVPPFLEVLDWESFAVFVPENEIPNLRKILISI |
Full Sequence |
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Protein Sequence Length: 544 Download |
MDQTRVFRFL CQVETCRVVF LMSLAVAFVL GLQYFEHAPI SIVSPENGTV SEFSESHDIT 60 KSAENETFLA PQEATSGFIP FNSTTEVLKS LEHKFLNYSP KASGESRGNG TASSLHSLQS 120 KIPRNNNKKH EHKRSTKKPP LVVISITQMN NMLWKRHSDP NNSLAPRWGS EVDKELKTAR 180 NKIKNAVLVN KDDTLYAPIY HNLSIFKRSY ELMEKTLKVY VYSEGDRPIF HQPEAIMEGV 240 YASEGWFMKL MESNSRFLTK DPTKAHLFYL AFNSRILQQK LYVRDSHRRR NLVKYLRDYI 300 NLIISKYPFW NRTRGSDHFF TACHDWAPAE TRGPYMNCIR SLCNADVGVD FIVGKDVSLP 360 ETKVSSSQTP NGNIGGNRPS KRTILAFFAG NLHGYVRPIL LNQWSSRPEP DMKIFNRIDH 420 KSYIRFMKRS RFCVCAKGYE VNSPRVVESV LYGCVPVIIS DNFVPPFLEV LDWESFAVFV 480 PENEIPNLRK ILISIPVRRY VEMQRRVLKV QKHFMWHDGE PVRYDLFHMI LHSVWYNRVF 540 QTF* 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-65 | 213 | 495 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42362.1 | 0 | 1 | 543 | 1 | 546 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_196722.1 | 0 | 1 | 543 | 1 | 546 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_974766.1 | 0 | 1 | 441 | 1 | 444 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002309547.1 | 0 | 131 | 541 | 56 | 467 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516500.1 | 0 | 139 | 542 | 51 | 453 | catalytic, putative [Ricinus communis] |