| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10013266m |
| Family | GT47 |
| Protein Properties | Length: 520 Molecular Weight: 59363.4 Isoelectric Point: 9.1582 |
| Chromosome | Chromosome/Scaffold: 2 Start: 5723872 End: 5727064 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 126 | 435 | 0 |
| IKVYVYEMPKKFTFDLLWLFHNTYKETSNATSNGSPVHRLIEQHSIDYWLWADLISPESERRLKSVVRVHHQQDADFFYVPFFTTISFFLLEKQQCKALY REALKWVTDQPAWKRSEGRDHIFPIHHPWSFKSVRKYVKNAIWLLPDMDSTGNWYKPGQVSLEKDLILPYVPNVDICDAKCLAESAPMRTTLLFFRGRLK RNAGGKIRAKLGAELSGVKDVIITEGTAGEGGKLAAQGGMRRSLFCLCPAGDTPSSARLFDAIVSGCIPVIVSDELELPFEGILDYKKVAVVVSSTDAIQ PGWLVNHLRS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 520 Download |
| MFGKQQNHHH HHHHHHAFSR PIIAKALVCI AFFLLLISLF VIPCIFLSFD RPSFSYPNQS 60 DRPETSFVAS LEQFLIHKAP KLSSPIRVDT ARGESDDDVR KLDEIVFERE SRWLNEDPGY 120 PIGFPIKVYV YEMPKKFTFD LLWLFHNTYK ETSNATSNGS PVHRLIEQHS IDYWLWADLI 180 SPESERRLKS VVRVHHQQDA DFFYVPFFTT ISFFLLEKQQ CKALYREALK WVTDQPAWKR 240 SEGRDHIFPI HHPWSFKSVR KYVKNAIWLL PDMDSTGNWY KPGQVSLEKD LILPYVPNVD 300 ICDAKCLAES APMRTTLLFF RGRLKRNAGG KIRAKLGAEL SGVKDVIITE GTAGEGGKLA 360 AQGGMRRSLF CLCPAGDTPS SARLFDAIVS GCIPVIVSDE LELPFEGILD YKKVAVVVSS 420 TDAIQPGWLV NHLRSLIPFQ VKDFQNSLAH YSRHFLYSSP AQPLGPEDLT WRMIAGKLVN 480 IKLHTRRTRR VVKGSRSICR CDCWRPNSTA YNSLSPLLS* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-65 | 125 | 435 | 319 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI20132.1 | 0 | 133 | 510 | 1 | 378 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197191.1 | 0 | 1 | 505 | 1 | 497 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002285599.1 | 0 | 63 | 510 | 62 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325382.1 | 0 | 57 | 510 | 51 | 502 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002520033.1 | 0 | 57 | 510 | 50 | 503 | catalytic, putative [Ricinus communis] |
