| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10013399m |
| Family | GT47 |
| Protein Properties | Length: 485 Molecular Weight: 55945.1 Isoelectric Point: 8.5093 |
| Chromosome | Chromosome/Scaffold: 2 Start: 3604106 End: 3606577 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 150 | 433 | 0 |
| EKRFKIWTYREGEAPLFHKGPLNNIYAIEGQFMDEIENGKSRFAAASPEEATVFYIPVGIVNIIRFVYRPYTSYARDRLQNIVKDYISLVSNRYPYWNRS RGADHFFLSCHDWAPDVSAVDPELYKHFIRALCNANSSEGFTPMRDVSLPEINIQYGQLGFVHDGEPPQNRKLLAFFAGGSHGEVRKILFEHWKEKDKDV LVYEYLPKTMNYTKMMDRAKFCLCPSGWEVASPRIVESLYSGCVPVIVADYYVLPFSDVLNWKSFSVHIPISKIPEIKKILEAI | |||
| Full Sequence |
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| Protein Sequence Length: 485 Download |
| MADLTCTTPF LLYPSLVIIL FFYSLNHHNR FLSSVVDDDP SCRLSLSSSN SSSPQSVFSS 60 FRFFPFRSSS SCLSTLNNSS SEVTVVEEVD EAVERIEEGL AMARAAIKKA KEVDLRRRRD 120 RRNNSNLRFA SNGSVYLNAF TFHQSHKEME KRFKIWTYRE GEAPLFHKGP LNNIYAIEGQ 180 FMDEIENGKS RFAAASPEEA TVFYIPVGIV NIIRFVYRPY TSYARDRLQN IVKDYISLVS 240 NRYPYWNRSR GADHFFLSCH DWAPDVSAVD PELYKHFIRA LCNANSSEGF TPMRDVSLPE 300 INIQYGQLGF VHDGEPPQNR KLLAFFAGGS HGEVRKILFE HWKEKDKDVL VYEYLPKTMN 360 YTKMMDRAKF CLCPSGWEVA SPRIVESLYS GCVPVIVADY YVLPFSDVLN WKSFSVHIPI 420 SKIPEIKKIL EAIPEEEYLK MQRGVLEVRK HFVVNRPSKP FDMLHMIMHS IWLRRLNVRI 480 PLSQ* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-63 | 149 | 433 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI21065.1 | 0 | 94 | 482 | 16 | 402 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_196674.1 | 0 | 149 | 484 | 1 | 336 | exostosin family protein [Arabidopsis thaliana] |
| Swiss-Prot | Q9LFP3 | 0 | 1 | 484 | 1 | 480 | GLYT4_ARATH RecName: Full=Probable glycosyltransferase At5g11130 |
| RefSeq | XP_002324873.1 | 0 | 149 | 481 | 1 | 334 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002515488.1 | 0 | 1 | 480 | 12 | 468 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EC939466 | 258 | 129 | 381 | 0 |
| FD507587 | 226 | 192 | 417 | 0 |
| EY926917 | 189 | 297 | 485 | 0 |
| GE475605 | 295 | 189 | 480 | 0 |
| EW739228 | 186 | 299 | 484 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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