| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10013464m |
| Family | GT47 |
| Protein Properties | Length: 466 Molecular Weight: 53289.3 Isoelectric Point: 10.159 |
| Chromosome | Chromosome/Scaffold: 2 Start: 7824302 End: 7826273 |
| Description | FRA8 homolog |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 109 | 409 | 0 |
| GMKIYIYDLPARFNVDWVTKSDRCATHLFAAEVAIHRALLSDSSVRTLDPEEADFFFVPVYVSCNFSTSNGFPSLSHARSLLGSAVDFLSDQYPFWNRTQ GSDHVFVASHDFGACFHAMEDMAIEEGIPEFMKKSIILQTFGVNYKHPCQEAEHVVIPPYIPPESVQRAMDRAPANGRRDIWAFFRGKMEVNPKNISGRF YSKGVRTAILKKYGGRRRFYLNRHRFAGYRSEIVRSVFCLCPLGWAPWSPRLVESAVLGCVPVVIADGIKLPFSETVRWPEISLTVAEKDVKNLRKILEH V | |||
| Full Sequence |
|---|
| Protein Sequence Length: 466 Download |
| MSLDIKRPNS NKTKKKMGFI VKMQLHNNNN RGGSNKRNLF FVFFRSYYRW ILWFFLSLYF 60 FTSYFAGDQS SPSSTTTTRL LSNHNPSSSL PSRALIESSA IVTPGIFSGM KIYIYDLPAR 120 FNVDWVTKSD RCATHLFAAE VAIHRALLSD SSVRTLDPEE ADFFFVPVYV SCNFSTSNGF 180 PSLSHARSLL GSAVDFLSDQ YPFWNRTQGS DHVFVASHDF GACFHAMEDM AIEEGIPEFM 240 KKSIILQTFG VNYKHPCQEA EHVVIPPYIP PESVQRAMDR APANGRRDIW AFFRGKMEVN 300 PKNISGRFYS KGVRTAILKK YGGRRRFYLN RHRFAGYRSE IVRSVFCLCP LGWAPWSPRL 360 VESAVLGCVP VVIADGIKLP FSETVRWPEI SLTVAEKDVK NLRKILEHVA VTNLSVIQRN 420 LREPAFKRAL LYNVPMKEGD ATWHILEALW RKLDRSYRRS RVLSE* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-73 | 108 | 406 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABI64067.1 | 0 | 36 | 462 | 16 | 439 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
| DDBJ | BAB10615.1 | 0 | 1 | 465 | 1 | 493 | unnamed protein product [Arabidopsis thaliana] |
| RefSeq | NP_197685.2 | 0 | 1 | 465 | 1 | 464 | F8H (FRA8 HOMOLOG); catalytic [Arabidopsis thaliana] |
| RefSeq | XP_002275679.1 | 0 | 3 | 454 | 2 | 441 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002314302.1 | 0 | 1 | 462 | 1 | 459 | predicted protein [Populus trichocarpa] |
