Basic Information | |
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Species | Thellungiella halophila |
Cazyme ID | Thhalv10015262m |
Family | AA3 |
Protein Properties | Length: 258 Molecular Weight: 28273.6 Isoelectric Point: 4.7659 |
Chromosome | Chromosome/Scaffold: 2 Start: 12901566 End: 12902422 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 38 | 242 | 1e-26 |
TLAPTHASFDYIIIGGGTSGCALAATLSQNANVLVLERGGSPYDNPTATDIGNFANTLLNITPNSWSQLFISEDGVYNTRPRVLGGGTVLNAGFYTRASG HYVEEAEWEMEEVEAAYEWVEKKLVFEPQVMGWQTAFKDGLLEAGVNPYNGFTYDHIYGTKIGGTILDGDGHRHTAANLLEYANPNNIVVYLHASVHKIF FTTTT |
Full Sequence |
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Protein Sequence Length: 258 Download |
MSFHILRLLR VILLAIFIFH GSCYSDEAGS YTFMKDATLA PTHASFDYII IGGGTSGCAL 60 AATLSQNANV LVLERGGSPY DNPTATDIGN FANTLLNITP NSWSQLFISE DGVYNTRPRV 120 LGGGTVLNAG FYTRASGHYV EEAEWEMEEV EAAYEWVEKK LVFEPQVMGW QTAFKDGLLE 180 AGVNPYNGFT YDHIYGTKIG GTILDGDGHR HTAANLLEYA NPNNIVVYLH ASVHKIFFTT 240 TTGTDYSYST SFNDQCK* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
COG0644 | FixC | 4.0e-6 | 45 | 83 | 40 | + Dehydrogenases (flavoproteins) [Energy production and conversion] |
TIGR01810 | betA | 3.0e-6 | 47 | 134 | 99 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. |
PRK02106 | PRK02106 | 8.0e-10 | 42 | 138 | 112 | + choline dehydrogenase; Validated |
COG2303 | BetA | 6.0e-12 | 40 | 134 | 101 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
PLN02785 | PLN02785 | 7.0e-83 | 26 | 236 | 212 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB11043.1 | 0 | 1 | 240 | 1 | 240 | mandelonitrile lyase-like protein [Arabidopsis thaliana] |
EMBL | CAB87405.1 | 0 | 1 | 239 | 1 | 239 | ADHESION OF CALYX EDGES-like protein [Arabidopsis thaliana] |
RefSeq | NP_001119417.1 | 0 | 34 | 254 | 1 | 222 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
RefSeq | NP_200008.1 | 0 | 1 | 254 | 1 | 255 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
RefSeq | NP_567032.1 | 0 | 1 | 239 | 1 | 239 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1ju2_B | 0 | 25 | 243 | 5 | 227 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 1ju2_A | 0 | 25 | 243 | 5 | 227 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_B | 0 | 25 | 243 | 5 | 227 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_A | 0 | 25 | 243 | 5 | 227 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdn_B | 0 | 25 | 243 | 5 | 227 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |