| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10015371m |
| Family | GT47 |
| Protein Properties | Length: 461 Molecular Weight: 52748.2 Isoelectric Point: 9.8982 |
| Chromosome | Chromosome/Scaffold: 2 Start: 6978356 End: 6981218 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 127 | 411 | 0 |
| EKKFKVWVYREGEPPLVHMGPVKGIYSIEGQFVDEMEREMSPFAASHPEEAHVFLLPVSITNIVHYVYRPLVTYSRKQLHQVFLDYVNVVAHKYPYWNSS LGADHFFVSCHDWAPDVSEANPEMLKNMIRVLCNANISEGFLPQRDVSIPEINIPGGHLGPPRLSRSSGHDRPILAFFAGGSHGPIRKVLLTHWKDKDEE VQVHEYLAHKKDYFKLMAKAKFCLCPSGYEVASPRVVSAINLGCVPVIISDHYALPFSDVLDWSKFTIHVPSDKIPEIKTILKSV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 461 Download |
| MKFSQAPSLL LLLLVILLFY QHHSSPNLNS KTLSSFAYAI SLAPSPSPSL SMRFSIPSSN 60 FTLISSADHK KEKKRNRIEE GLAKSRAAIR EAVRSKKYAS EKEETFVPRG AVYRNAYAFH 120 QSHIEMEKKF KVWVYREGEP PLVHMGPVKG IYSIEGQFVD EMEREMSPFA ASHPEEAHVF 180 LLPVSITNIV HYVYRPLVTY SRKQLHQVFL DYVNVVAHKY PYWNSSLGAD HFFVSCHDWA 240 PDVSEANPEM LKNMIRVLCN ANISEGFLPQ RDVSIPEINI PGGHLGPPRL SRSSGHDRPI 300 LAFFAGGSHG PIRKVLLTHW KDKDEEVQVH EYLAHKKDYF KLMAKAKFCL CPSGYEVASP 360 RVVSAINLGC VPVIISDHYA LPFSDVLDWS KFTIHVPSDK IPEIKTILKS VSWRRYLVLQ 420 RRVLQVQRHF VINRPSQPFD MLRMLLHSVW LRRLNLRLPM * 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-62 | 126 | 411 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI25529.1 | 0 | 77 | 458 | 6 | 386 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197526.4 | 0 | 52 | 459 | 1 | 408 | catalytic [Arabidopsis thaliana] |
| Swiss-Prot | Q3E9A4 | 0 | 19 | 459 | 26 | 466 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
| RefSeq | XP_002515488.1 | 0 | 7 | 458 | 25 | 468 | catalytic, putative [Ricinus communis] |
| RefSeq | XP_002531945.1 | 0 | 1 | 460 | 5 | 452 | catalytic, putative [Ricinus communis] |
