| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10016080m |
| Family | GT47 |
| Protein Properties | Length: 518 Molecular Weight: 58305 Isoelectric Point: 9.4675 |
| Chromosome | Chromosome/Scaffold: 2 Start: 994465 End: 997544 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 186 | 467 | 0 |
| EKQFKIFVYKEGEPPLFHDGPCKSIYSMEGNFIYEMETDTRFRTNNPDKAHAFYLPLSVVKMVRYVYVSNSHDFSPIRKTVRDYIDLVSDKYSYWNRSIG ADHFILSCHDWGPEASFSHPHLGQNSIRALCNANTSERFKPRKDVSIPEINLRTGSLKGLVGGPSPSSRPILAFFAGGVHGPVRPVLLQHWENKDNDIRV HKYLPRGTSYSDMMRNSKFCICPSGYEVASPRIVEALYSGCVPVLINSGYVPPFSDVLNWRSFSVIVSVEDIPNLKTILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 518 Download |
| MGDEDVNGKC RIMSACSSAK LFLFMVPLVI VSCFVFVNIG PKNPSSFLTS LSTNHLSPPL 60 LPSSPYLPPA PAPAPSPLQA ATGLLSPASS LSTKVEFFQG DNNRTVGLNP INITSASNNV 120 TSTASSEQIK KRVMSNLEKI EFELQKARVA IKAASMDDPV DDPDYVPLGP MYWNAKVFHR 180 SYLEMEKQFK IFVYKEGEPP LFHDGPCKSI YSMEGNFIYE METDTRFRTN NPDKAHAFYL 240 PLSVVKMVRY VYVSNSHDFS PIRKTVRDYI DLVSDKYSYW NRSIGADHFI LSCHDWGPEA 300 SFSHPHLGQN SIRALCNANT SERFKPRKDV SIPEINLRTG SLKGLVGGPS PSSRPILAFF 360 AGGVHGPVRP VLLQHWENKD NDIRVHKYLP RGTSYSDMMR NSKFCICPSG YEVASPRIVE 420 ALYSGCVPVL INSGYVPPFS DVLNWRSFSV IVSVEDIPNL KTILTSISPR QYLRMYRRVL 480 KVRRHFEVNS PAKRFDVFHM ILHSIWVRRL NVRIREV* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-68 | 185 | 467 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB08605.1 | 0 | 111 | 517 | 2 | 408 | unnamed protein product [Arabidopsis thaliana] |
| RefSeq | NP_001031828.1 | 0 | 1 | 517 | 1 | 518 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002284018.1 | 0 | 185 | 516 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002326234.1 | 0 | 185 | 512 | 1 | 328 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002528630.1 | 0 | 100 | 516 | 155 | 567 | catalytic, putative [Ricinus communis] |
