| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10016337m |
| Family | GT47 |
| Protein Properties | Length: 691 Molecular Weight: 80226.9 Isoelectric Point: 8.6114 |
| Chromosome | Chromosome/Scaffold: 10 Start: 4530936 End: 4533379 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 259 | 598 | 0 |
| CAGKYVYMHEVPALFNEELLKNCWTLSKWTDMCELTSNFGLGPRLPNMEGVSGWFATNQFTLEVIFHNRMKQYKCLTKDSSLASAVYVPYYPGLDLMRFL WGPFPFMRDAAALDLMKWLRERPEWKRMDGRDHFMVAGRTTWDFMRTPENESDWGNRLMILPEIRNMTMLLIESSPWNYHGFAVPYPTYFHPSTNAEILQ WQNRMRRIKRRYLFSFVGAPRPNLGDSIRSEIMDQCKASRRKCKLLECVSGSQKCYKPDQIMKFFLSSTFCLQPPGDSYTRRSTFDSILAGCIPVFFHPG SAYAQYIWHLPKDISKYSVFIPGKNVKEGKASIEKILSRI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 691 Download |
| MAMEKSSSKY RTQFWYVAIA SFLLWLFLLY LFNSSAKTVH SHERLFRQEN VIDLVPEHHE 60 SDQPVVSGVD NKTLPVPGDD SSPEDRISED AKVVNDLVEE LEKEKVESEK KRGGSVLSGR 120 STRARRGHRE PRKSRSSSRA EEEKKRVRSN ADDVERNVDN SDQSFDKEPS FLEAKKERVD 180 DDNNDLESKG GNELPNDWSN NDLEGDNTSE TVPEQKIQSN LALNNSTSEA RNRLISKRNQ 240 PRRVRNVIVR PKTRRNDPCA GKYVYMHEVP ALFNEELLKN CWTLSKWTDM CELTSNFGLG 300 PRLPNMEGVS GWFATNQFTL EVIFHNRMKQ YKCLTKDSSL ASAVYVPYYP GLDLMRFLWG 360 PFPFMRDAAA LDLMKWLRER PEWKRMDGRD HFMVAGRTTW DFMRTPENES DWGNRLMILP 420 EIRNMTMLLI ESSPWNYHGF AVPYPTYFHP STNAEILQWQ NRMRRIKRRY LFSFVGAPRP 480 NLGDSIRSEI MDQCKASRRK CKLLECVSGS QKCYKPDQIM KFFLSSTFCL QPPGDSYTRR 540 STFDSILAGC IPVFFHPGSA YAQYIWHLPK DISKYSVFIP GKNVKEGKAS IEKILSRIPR 600 GKVVAMREEV IRLIPRLMYF NPSGKRGDVG RFEDAFDVAV EGVLQRVEGL RKKIEEGNEE 660 IFDFPEQFSW KYNVFGNVER HEWDSYFDRP * 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-65 | 258 | 598 | 354 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACY08857.1 | 0 | 249 | 690 | 147 | 591 | xyloglucan galactosyltransferase [Eucalyptus grandis] |
| EMBL | CAN64889.1 | 0 | 9 | 670 | 15 | 710 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_180468.1 | 0 | 1 | 690 | 1 | 720 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002280815.1 | 0 | 256 | 689 | 90 | 523 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313430.1 | 0 | 236 | 689 | 122 | 569 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
