y
Basic Information | |
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Species | Thellungiella halophila |
Cazyme ID | Thhalv10016613m |
Family | GT47 |
Protein Properties | Length: 466 Molecular Weight: 53219.2 Isoelectric Point: 9.9525 |
Chromosome | Chromosome/Scaffold: 10 Start: 6637461 End: 6639590 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 61 | 409 | 0 |
RFVYIHNLPSRFNTDILQDCESISRPKDKISMCKYLDNFGFGPLIGDGVSTDSQYYSPSWYATNQFMLEVIFHEKMKRYECLTLNSSLASAIYVPYYAGL DFRRNLRRRNVAARDAAGKELVKWLKKQPQWTGMSGKDHFLVTGRISRDFQRNSDNKSGWGTNLMLLPESQNLSFLTIERNPTSHNEFSIPYPTYFHPNS AVEILKWQNKIKLTNRTILFSFAGAQRPSRSKNGLVRTQVIQQCKTSSKTCRFLDCDVKSSSCDDPISLMKLFESSVFCLQPPGDSLTRRSVFDSILAGC IPVFFNQGSAYKQYVWHIPSNNSDYSVYIPVKELRTGGKNKIQEILRRI |
Full Sequence |
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Protein Sequence Length: 466 Download |
MKKKPTTLFL LLSLLTISLL LLRLSQTKII HITTTTTTTS DSDHHHRYKP AGLGDDPCLG 60 RFVYIHNLPS RFNTDILQDC ESISRPKDKI SMCKYLDNFG FGPLIGDGVS TDSQYYSPSW 120 YATNQFMLEV IFHEKMKRYE CLTLNSSLAS AIYVPYYAGL DFRRNLRRRN VAARDAAGKE 180 LVKWLKKQPQ WTGMSGKDHF LVTGRISRDF QRNSDNKSGW GTNLMLLPES QNLSFLTIER 240 NPTSHNEFSI PYPTYFHPNS AVEILKWQNK IKLTNRTILF SFAGAQRPSR SKNGLVRTQV 300 IQQCKTSSKT CRFLDCDVKS SSCDDPISLM KLFESSVFCL QPPGDSLTRR SVFDSILAGC 360 IPVFFNQGSA YKQYVWHIPS NNSDYSVYIP VKELRTGGKN KIQEILRRIP NEKVIGMREN 420 VIRLVPKIMY TKPNRHKPDG ETLEDAFDVA VKEVVKIIQG TRREI* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-59 | 57 | 409 | 364 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD15405.1 | 0 | 2 | 463 | 25 | 481 | hypothetical protein [Arabidopsis thaliana] |
RefSeq | NP_180759.2 | 0 | 2 | 463 | 17 | 473 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_180833.1 | 0 | 5 | 456 | 25 | 458 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_193135.2 | 0 | 34 | 462 | 71 | 488 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002280815.1 | 0 | 56 | 465 | 91 | 487 | PREDICTED: hypothetical protein [Vitis vinifera] |