| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10016649m |
| Family | GT47 |
| Protein Properties | Length: 451 Molecular Weight: 51423.2 Isoelectric Point: 9.5113 |
| Chromosome | Chromosome/Scaffold: 10 Start: 3362460 End: 3364768 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 95 | 395 | 0 |
| NLKIYVYDLPSKFNTDWLANDRCSNHLFAAEVALHKALLSLDGDVRTEDPYEADFFFVPVYVSCNFSTINGFPAIGHARSLIKEAIGLVSTQYPFWNRTS GSDHVFIATHDFGSCFHTMEDRAIADGVPKILRNSIVLQTFGVTFKHPCQEVENIVIPPYISPESLHKTQKNIPVAKERDIWVFFRGKMEIHPKNISGRF YSKRIRTKIWRSYGGDRRFYLQRQRFAGYQSEIARSVFCLCPLGWAPWSPRLVESVALGCVPVIIADGIRLPFPSAMRWPEISLTVAEKDVGKLGEILEH V | |||
| Full Sequence |
|---|
| Protein Sequence Length: 451 Download |
| MITQKQRRAE KSLCLKNYYK WILCFSLTLY FLASFFVDHD QEDHPLSSSS RSNPLLTNPK 60 PKLLASRAVF ESKIHDNTLG FAPQRPNIRT DVFNNLKIYV YDLPSKFNTD WLANDRCSNH 120 LFAAEVALHK ALLSLDGDVR TEDPYEADFF FVPVYVSCNF STINGFPAIG HARSLIKEAI 180 GLVSTQYPFW NRTSGSDHVF IATHDFGSCF HTMEDRAIAD GVPKILRNSI VLQTFGVTFK 240 HPCQEVENIV IPPYISPESL HKTQKNIPVA KERDIWVFFR GKMEIHPKNI SGRFYSKRIR 300 TKIWRSYGGD RRFYLQRQRF AGYQSEIARS VFCLCPLGWA PWSPRLVESV ALGCVPVIIA 360 DGIRLPFPSA MRWPEISLTV AEKDVGKLGE ILEHVAATNL SIIQKNLEDP SIRRALMFNV 420 PPREGDATWQ VLEALSKKLS RSTRRSNAFM * 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-71 | 96 | 392 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33322.1 | 0 | 5 | 444 | 11 | 435 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| GenBank | ABI64067.1 | 0 | 5 | 444 | 11 | 435 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
| RefSeq | NP_850113.2 | 0 | 1 | 450 | 1 | 448 | FRA8 (FRAGILE FIBER 8); glucuronosyltransferase/ transferase [Arabidopsis thaliana] |
| RefSeq | XP_002314302.1 | 0 | 5 | 444 | 31 | 455 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523710.1 | 0 | 4 | 444 | 28 | 454 | transferase, putative [Ricinus communis] |
