| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10016654m |
| Family | GT47 |
| Protein Properties | Length: 447 Molecular Weight: 50979.6 Isoelectric Point: 9.1933 |
| Chromosome | Chromosome/Scaffold: 10 Start: 8054258 End: 8056255 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 58 | 370 | 0 |
| RVRVYMYDLPRRFTYGVIEQHAIVRGGLKKPVDDVATLKYPGHQHMHEWYLFSDLNRPEVDRSGSPITRVMDPADADLFYVPVFSSLSLIVNAGRPVEPG SGYSDEKMQEGLMEWLERQEWWRRNEGRDHVIPAGDPNALYRILDRVKNAVLLVADFGRLRPDQGSFVKDVVIPYSHRVNLFNGEIGVESRNTLLFFMGN RYRKDGGKVRDLLFQVLEKEEDVTIKHGTQSRENRRAATKGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPVIVSDSIELPFEDVIDYRKFSIFVEANAA LEPGFLVQMLRKI | |||
| Full Sequence |
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| Protein Sequence Length: 447 Download |
| MARKSSLLKR AAIAVVSVIA IYVILNASVS RSLPSSSDLP RQLFRDEDDE GRAPIQPRVR 60 VYMYDLPRRF TYGVIEQHAI VRGGLKKPVD DVATLKYPGH QHMHEWYLFS DLNRPEVDRS 120 GSPITRVMDP ADADLFYVPV FSSLSLIVNA GRPVEPGSGY SDEKMQEGLM EWLERQEWWR 180 RNEGRDHVIP AGDPNALYRI LDRVKNAVLL VADFGRLRPD QGSFVKDVVI PYSHRVNLFN 240 GEIGVESRNT LLFFMGNRYR KDGGKVRDLL FQVLEKEEDV TIKHGTQSRE NRRAATKGMH 300 TSKFCLNPAG DTPSACRLFD SIVSLCVPVI VSDSIELPFE DVIDYRKFSI FVEANAALEP 360 GFLVQMLRKI KTKKILEYQR EMQSVRRYFD YENPNGAVKE IWRQVSQKLP LIKLMSNRDK 420 RLVLRNLTEP NCSCLCTNQT GLITSI* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-81 | 55 | 370 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC61825.1 | 0 | 1 | 384 | 1 | 385 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_199306.1 | 0 | 9 | 446 | 14 | 443 | ARAD2 (ARABINAN DEFICIENT 2); catalytic [Arabidopsis thaliana] |
| RefSeq | NP_850241.1 | 0 | 1 | 446 | 1 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002322391.1 | 0 | 1 | 446 | 1 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523645.1 | 0 | 1 | 446 | 1 | 452 | catalytic, putative [Ricinus communis] |
