| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10017561m |
| Family | GT47 |
| Protein Properties | Length: 505 Molecular Weight: 58838.1 Isoelectric Point: 9.8864 |
| Chromosome | Chromosome/Scaffold: 10 Start: 6957904 End: 6959418 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 83 | 430 | 0 |
| CAGRYIYMHNLPSRFNDDIIKNCRTLIKWFDMCPFMVNSGLGPQVTESNNKTARILPVKTGSWYSTNQFLLAVIFRERMKHYKCLTNDSSLASAIYVPFY AGFDVSRHLWGYNTTVRDELGTKLGLWLRERPEWRKMYGRDHFFVTGRIAWDFRRGLDDDSEWGSKLMLLPEFANMTMLSIETTAWANEFAIPYPTYFHP KRFNEVLRWQRKMRNVKRRHLFSFVGAPRPKMNGSIRGEIIKQCLASHGKCKYLNCFVSGKECDNPVKIIEVFQHSVFCLQPPGDSYTRRSIFDSILAGC IPVFFHPGSGYNQYMWYFPKDYTKYSVYVPEKGMRNGTVSLMELLGRI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 505 Download |
| MMKPVPRLWI VISTTFAFCL FVLFQVHNSD LIRKNPQITH QVNNFFISIA SSSHHQTLNL 60 TKIANESDGN RAKQPEEERT DTCAGRYIYM HNLPSRFNDD IIKNCRTLIK WFDMCPFMVN 120 SGLGPQVTES NNKTARILPV KTGSWYSTNQ FLLAVIFRER MKHYKCLTND SSLASAIYVP 180 FYAGFDVSRH LWGYNTTVRD ELGTKLGLWL RERPEWRKMY GRDHFFVTGR IAWDFRRGLD 240 DDSEWGSKLM LLPEFANMTM LSIETTAWAN EFAIPYPTYF HPKRFNEVLR WQRKMRNVKR 300 RHLFSFVGAP RPKMNGSIRG EIIKQCLASH GKCKYLNCFV SGKECDNPVK IIEVFQHSVF 360 CLQPPGDSYT RRSIFDSILA GCIPVFFHPG SGYNQYMWYF PKDYTKYSVY VPEKGMRNGT 420 VSLMELLGRI DKRRISKMRN EVTKIIPKII YTKPGLVGPE KIEDAFEIAV DRVLERVAMV 480 KRMMEEGKNL QSEYSQNRDL KKLE* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-63 | 83 | 430 | 363 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_180833.1 | 0 | 51 | 481 | 45 | 464 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_180834.1 | 0 | 1 | 504 | 1 | 502 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002321098.1 | 0 | 35 | 501 | 7 | 462 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002518606.1 | 0 | 80 | 489 | 73 | 472 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
| RefSeq | XP_002532518.1 | 0 | 1 | 501 | 1 | 518 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
