| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10017970m |
| Family | GT47 |
| Protein Properties | Length: 326 Molecular Weight: 37357.2 Isoelectric Point: 6.9293 |
| Chromosome | Chromosome/Scaffold: 10 Start: 5528355 End: 5530595 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 26 | 175 | 3.5e-31 |
| RLKVFVYELPSKYNKKILQKDPRCLTHMFAAEIYIERFLLSSPVRTLNPEEADWFDVPVYTTCEMMRSAIQLIASNWPYWNRTEGAGHFFVVPHDFGPCF LYQEEKSIGSGILPLLQRATQVQTFGQRNHVCLKEGSITVPRYAPPQKMQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 326 Download |
| MKFSSWVLIF LVCSAGDVLE DDPVGRLKVF VYELPSKYNK KILQKDPRCL THMFAAEIYI 60 ERFLLSSPVR TLNPEEADWF DVPVYTTCEM MRSAIQLIAS NWPYWNRTEG AGHFFVVPHD 120 FGPCFLYQEE KSIGSGILPL LQRATQVQTF GQRNHVCLKE GSITVPRYAP PQKMQSRENS 180 SIHLPVWENF KDNPLFDIST EHPATYYEDM QRAIFCLCPL GWASWSPRLV EAVIFDIGVF 240 VDEKDVPYLD TILTSIPPEV ILRKQRLLAN PSMKQAMLFP QPGNAFHQLL NGLARKLPHE 300 RNVYLRPGEK LLNWTAGPVA DLKPW* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-49 | 26 | 256 | 296 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM64940.1 | 0 | 1 | 325 | 1 | 415 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_568941.1 | 0 | 1 | 325 | 1 | 415 | GUT1; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002284685.1 | 0 | 14 | 325 | 37 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318180.1 | 0 | 14 | 325 | 38 | 417 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511079.1 | 0 | 14 | 325 | 38 | 417 | catalytic, putative [Ricinus communis] |
