Basic Information | |
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Species | Thellungiella halophila |
Cazyme ID | Thhalv10018360m |
Family | AA3 |
Protein Properties | Length: 555 Molecular Weight: 61283 Isoelectric Point: 9.2951 |
Chromosome | Chromosome/Scaffold: 9 Start: 3301034 End: 3303183 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 49 | 549 | 0 |
ASEDYYDYIIVGGGTAGCPLAATLSQSFRVLLLERGGVPYNRPHVMSHDGFLTTLTDVNNFDSPAQSFISEEGVPNARGRVLGGSSAINAGFYSRADKQF FENSGLNWDLTTVNQSYEWVERAIVFRPQLRTWQSAIRDALLEVGVHPFNGFTLEHKVGTKIGGSTFDRAGRRHSSADLLRYSRSSNIRVAVYATVERVL LASSPSDSGSNVSAIGVVYRDQLGRYHHALIRDRGEVILSAGSLGSPQLLLLSGIGTRSYLSTWGIPVALDQPHVGDFVYDNPRNGISIVPPVPMESSLI QVVGITEEGAFLEAASNVIPFASPIHSVFIRAPASPLYVPVTTIMEKILGPVSTGSLRLASTDVRINPIVRFNYFSDPQDLERCVNGTRKIGEILRSRAM QDFMFREWFGSRRFRFVGVPLPVDQSNDLVMAEFCRRTVSTIWHYHGGCVVGKVVNSDLKVIGIDSLRIVDGSTFNISPGTNPQATLMMLGRYMGLQMLR E |
Full Sequence |
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Protein Sequence Length: 555 Download |
MSKRMDCYLL YTVFVVLLLL GAVSQSNARP RANRPPNFMR FVTNATDFAS EDYYDYIIVG 60 GGTAGCPLAA TLSQSFRVLL LERGGVPYNR PHVMSHDGFL TTLTDVNNFD SPAQSFISEE 120 GVPNARGRVL GGSSAINAGF YSRADKQFFE NSGLNWDLTT VNQSYEWVER AIVFRPQLRT 180 WQSAIRDALL EVGVHPFNGF TLEHKVGTKI GGSTFDRAGR RHSSADLLRY SRSSNIRVAV 240 YATVERVLLA SSPSDSGSNV SAIGVVYRDQ LGRYHHALIR DRGEVILSAG SLGSPQLLLL 300 SGIGTRSYLS TWGIPVALDQ PHVGDFVYDN PRNGISIVPP VPMESSLIQV VGITEEGAFL 360 EAASNVIPFA SPIHSVFIRA PASPLYVPVT TIMEKILGPV STGSLRLAST DVRINPIVRF 420 NYFSDPQDLE RCVNGTRKIG EILRSRAMQD FMFREWFGSR RFRFVGVPLP VDQSNDLVMA 480 EFCRRTVSTI WHYHGGCVVG KVVNSDLKVI GIDSLRIVDG STFNISPGTN PQATLMMLGR 540 YMGLQMLRER MRYK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR01810 | betA | 2.0e-23 | 55 | 539 | 555 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
TIGR03970 | Rv0697 | 6.0e-25 | 55 | 539 | 535 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
pfam05199 | GMC_oxred_C | 1.0e-28 | 399 | 539 | 146 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
COG2303 | BetA | 4.0e-30 | 54 | 540 | 553 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 5.0e-178 | 30 | 551 | 557 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABE65766.1 | 0 | 1 | 552 | 1 | 552 | mandelonitrile lyase [Arabidopsis thaliana] |
RefSeq | NP_177448.1 | 0 | 1 | 552 | 1 | 552 | (R)-mandelonitrile lyase, putative / (R)-oxynitrilase, putative [Arabidopsis thaliana] |
Swiss-Prot | P52706 | 0 | 32 | 550 | 32 | 544 | MDL1_PRUSE RecName: Full=(R)-mandelonitrile lyase 1; AltName: Full=Hydroxynitrile lyase 1; Short=(R)-oxynitrilase 1; Flags: Precursor |
RefSeq | XP_002277531.1 | 0 | 14 | 552 | 11 | 548 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311915.1 | 0 | 36 | 550 | 2 | 517 | predicted protein [Populus trichocarpa] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 37 | 550 | 10 | 517 | A Chain A, Crystal Structure Of (+)-Delta-Cadinene Synthase From Gossypium Arboreum And Evolutionary Divergence Of Metal Binding Motifs For Catalysis |
PDB | 3gdp_A | 0 | 37 | 550 | 10 | 517 | A Chain A, Crystal Structure Of (+)-Delta-Cadinene Synthase From Gossypium Arboreum And Evolutionary Divergence Of Metal Binding Motifs For Catalysis |
PDB | 3gdn_B | 0 | 37 | 550 | 10 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 37 | 550 | 10 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 37 | 550 | 10 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |