| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10018515m |
| Family | GT47 |
| Protein Properties | Length: 460 Molecular Weight: 52595.1 Isoelectric Point: 9.7658 |
| Chromosome | Chromosome/Scaffold: 9 Start: 2608002 End: 2609706 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 74 | 392 | 0 |
| VLKVFMYDLPPEFHFGILNWHRKGSEIWPNVKNISTIPSYPGGLNRQHSAEYWLTLDLLASETPEIKRPCTAIRVKNSIEADIVFVPFFSSLSYNRKSKL RGNETTSVDKLLQERLVEFLKSQEEWKRFNGRDHLIIAHHPNSLLYARNSLGSAMFVLSDFGRYPSSIANLEKDVIAPYFHVVKTIPNNESATFENRPVL AYFQGAIYRKDGGTIRQELYNLLKDEKDVHFAFGTVKGNGTKQTGKGMASSKFCLNIAGDTPSSNRLFDSIVSHCVPVIISDQIELPFEDTLDYSGFSVF VHSSEAVKKGLLVNLLRGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 460 Download |
| MSEKSLLSSK FLFYTVTVST LLFILSSLFF LQRNESSFTS TLVRKLILPR TDIKNEGFRK 60 TDSKPVSCGL NRDVLKVFMY DLPPEFHFGI LNWHRKGSEI WPNVKNISTI PSYPGGLNRQ 120 HSAEYWLTLD LLASETPEIK RPCTAIRVKN SIEADIVFVP FFSSLSYNRK SKLRGNETTS 180 VDKLLQERLV EFLKSQEEWK RFNGRDHLII AHHPNSLLYA RNSLGSAMFV LSDFGRYPSS 240 IANLEKDVIA PYFHVVKTIP NNESATFENR PVLAYFQGAI YRKDGGTIRQ ELYNLLKDEK 300 DVHFAFGTVK GNGTKQTGKG MASSKFCLNI AGDTPSSNRL FDSIVSHCVP VIISDQIELP 360 FEDTLDYSGF SVFVHSSEAV KKGLLVNLLR GITEDQWKKK WERLKEVVRF FEYRFPSQPG 420 DSVDLIWSSV SHKLSSLHFG VQRKNRYHRS EIFDRNQST* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-59 | 75 | 392 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD55303.1 | 0 | 1 | 459 | 1 | 458 | AC008263_34 F25A4.34 [Arabidopsis thaliana] |
| RefSeq | NP_565089.1 | 0 | 1 | 459 | 4 | 461 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002284930.1 | 0 | 1 | 453 | 1 | 451 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002284932.1 | 0 | 50 | 453 | 15 | 412 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
| RefSeq | XP_002514760.1 | 0 | 67 | 452 | 104 | 489 | catalytic, putative [Ricinus communis] |
