| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10018517m |
| Family | GT47 |
| Protein Properties | Length: 459 Molecular Weight: 52719.5 Isoelectric Point: 8.2874 |
| Chromosome | Chromosome/Scaffold: 9 Start: 5819215 End: 5821009 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 73 | 407 | 0 |
| NFTVYVYDLPKEFNTNLLQNCRHLNIYTDMCPHVANNGLGQPLRRDSKTWFATHQFIAEMIFHARVENHPCRTLEPSNADIFYVPFYGGLYGSSVFREHN LTKRDEVAVRLVDYVSGQRWWKKSNGRDHFLAIGRTAWDFMRASDEAGTDFGANTLMVMPRVMNMSVLTVERQPWKGDNQFGIPYPSYFHPYTSAEMVTW QDKMRIVERPHLFSFVGGPRKGLEKAAIRDELIRQCAGSSRCELLKCESGGTRCHDPMTVLGVMARSRFCLQAPGDSFTRRSTFDAMLAGCIPVFFSPHT MYTQYMWYLPDDRRSYSVFMDEKNSTQIEHELSRI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 459 Download |
| MSYTKKHAKI DQWPEKEKEK YTKNRETLKL TIPTLLLFCS VCLIFLILLF PFTSPPQTTS 60 FPASSLPRTC FQNFTVYVYD LPKEFNTNLL QNCRHLNIYT DMCPHVANNG LGQPLRRDSK 120 TWFATHQFIA EMIFHARVEN HPCRTLEPSN ADIFYVPFYG GLYGSSVFRE HNLTKRDEVA 180 VRLVDYVSGQ RWWKKSNGRD HFLAIGRTAW DFMRASDEAG TDFGANTLMV MPRVMNMSVL 240 TVERQPWKGD NQFGIPYPSY FHPYTSAEMV TWQDKMRIVE RPHLFSFVGG PRKGLEKAAI 300 RDELIRQCAG SSRCELLKCE SGGTRCHDPM TVLGVMARSR FCLQAPGDSF TRRSTFDAML 360 AGCIPVFFSP HTMYTQYMWY LPDDRRSYSV FMDEKNSTQI EHELSRISDS EVVMLRETII 420 NLIPSMTYAH PNATNYDLLD AVDVALEALA KQARGKVV* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-75 | 74 | 407 | 348 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC42883.1 | 0 | 1 | 458 | 1 | 452 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_177014.1 | 0 | 1 | 458 | 1 | 452 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002270383.1 | 0 | 76 | 457 | 125 | 503 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300452.1 | 0 | 70 | 449 | 1 | 391 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002336132.1 | 0 | 57 | 449 | 11 | 412 | predicted protein [Populus trichocarpa] |
