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Basic Information | |
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Species | Thellungiella halophila |
Cazyme ID | Thhalv10020554m |
Family | GT47 |
Protein Properties | Length: 507 Molecular Weight: 57427.3 Isoelectric Point: 9.9034 |
Chromosome | Chromosome/Scaffold: 13 Start: 8789623 End: 8793159 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 113 | 422 | 0 |
VKVYVYKMPKKFTYDLLWLFHNTYKETSNLTSNGSPVHRLIEQHSIDYWLWAELIAPESERRLKSVVRVHKQQDADIFYVPFFTTISFFLLEKQQCKALY REALKWITDQPAWKRSEGRDHVFPIHHPWSFKSVRKFVKNAIWLLPDLDSTGNWYKPGQVSLEKDLILPYVPNVDLCDAKCLSENSPKRTTLLFFRGRLK RNAGGKVRAKLGAELSSAKDVIITEGTAGDEGKLAAQKGMRRSLFCLCPAGDTPSSARLFDAIVSGCIPVVVSDELELPFEGLLDYRKIAVIVSSGDATQ PGWLVNHLRS |
Full Sequence |
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Protein Sequence Length: 507 Download |
MPGKLHNRHS SSRCNLRFVI LAAAPAVAVV FILFICSVYF SSVRPSVTYS VQTERSFVAS 60 LEHFLTHKAP KLSSHVIDDT VRGESDHLAR KLDDLVFERE NRLLNEDPVG FPVKVYVYKM 120 PKKFTYDLLW LFHNTYKETS NLTSNGSPVH RLIEQHSIDY WLWAELIAPE SERRLKSVVR 180 VHKQQDADIF YVPFFTTISF FLLEKQQCKA LYREALKWIT DQPAWKRSEG RDHVFPIHHP 240 WSFKSVRKFV KNAIWLLPDL DSTGNWYKPG QVSLEKDLIL PYVPNVDLCD AKCLSENSPK 300 RTTLLFFRGR LKRNAGGKVR AKLGAELSSA KDVIITEGTA GDEGKLAAQK GMRRSLFCLC 360 PAGDTPSSAR LFDAIVSGCI PVVVSDELEL PFEGLLDYRK IAVIVSSGDA TQPGWLVNHL 420 RSLSPSHIKG LQKNVAKYSR HFLYSSPAQP LGPEDLTWRM IAGKVVSMKL HTRRSQRMVK 480 GSRSICRCDC WQPNSTVSNP LTRVLS* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-61 | 124 | 422 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EAY76230.1 | 0 | 45 | 494 | 53 | 506 | hypothetical protein OsI_04166 [Oryza sativa Indica Group] |
RefSeq | NP_197191.1 | 0 | 1 | 492 | 1 | 497 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002285599.1 | 0 | 54 | 496 | 63 | 511 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325382.1 | 0 | 50 | 497 | 54 | 502 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002520033.1 | 0 | 45 | 496 | 48 | 502 | catalytic, putative [Ricinus communis] |