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Basic Information | |
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Species | Thellungiella halophila |
Cazyme ID | Thhalv10020580m |
Family | GT47 |
Protein Properties | Length: 498 Molecular Weight: 57215.3 Isoelectric Point: 9.2994 |
Chromosome | Chromosome/Scaffold: 13 Start: 8578883 End: 8580758 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 115 | 432 | 0 |
PLKVYMYDMSPEYHFGLLGWKPERNDVVWPDIRTNVPYHPGGLNLQHSVEYWLTLDLLYSELPEDSRTSRAAIRVKNSSEADVVFVPFFSSLSYNRFSKV TQKQTKSQDRVLQENVVKFVTGQKEWKMTGGKNHVILAHHPNSMSTARHKLYPAMFVVADFGRYSPRVANVDKDIVAPYKHLVPSYANDSSGFDGRPILL YFQGAIYRKAGGFVRHELYELLKEEKDVHFSFGSVRNHGITKAGEGMRSSKFCLNIAGDTPSSNRLFDAIASHCIPVIISDDIELPYEDVLNYNEFCLFV RSSDALKKGFLMGLVRSI |
Full Sequence |
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Protein Sequence Length: 498 Download |
MVERSNSRYQ RTIITPKSMI FLFILILSVL SWFLIFSSTN PNRVLDYISV SEPTDALVNI 60 IKNSNDPPQE KDAESPNPEN REDENRGGVK TEEAINENRG ETLRCIQKGS PSPAPLKVYM 120 YDMSPEYHFG LLGWKPERND VVWPDIRTNV PYHPGGLNLQ HSVEYWLTLD LLYSELPEDS 180 RTSRAAIRVK NSSEADVVFV PFFSSLSYNR FSKVTQKQTK SQDRVLQENV VKFVTGQKEW 240 KMTGGKNHVI LAHHPNSMST ARHKLYPAMF VVADFGRYSP RVANVDKDIV APYKHLVPSY 300 ANDSSGFDGR PILLYFQGAI YRKAGGFVRH ELYELLKEEK DVHFSFGSVR NHGITKAGEG 360 MRSSKFCLNI AGDTPSSNRL FDAIASHCIP VIISDDIELP YEDVLNYNEF CLFVRSSDAL 420 KKGFLMGLVR SIGREEWNKM WRRLKEVERY FDLRFPAKDD DRDYGVQMIW KAVARKAPLV 480 KMKVHRFQRF TRPFLMV* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-56 | 112 | 432 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 116 | 492 | 119 | 490 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | NP_187015.1 | 0 | 1 | 494 | 1 | 499 | EDA5 (embryo sac development arrest 5); catalytic [Arabidopsis thaliana] |
RefSeq | NP_190126.1 | 0 | 1 | 491 | 3 | 454 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002319201.1 | 0 | 1 | 491 | 3 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 37 | 494 | 38 | 483 | catalytic, putative [Ricinus communis] |