| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10020696m |
| Family | GT47 |
| Protein Properties | Length: 460 Molecular Weight: 53423.5 Isoelectric Point: 8.6564 |
| Chromosome | Chromosome/Scaffold: 13 Start: 6962772 End: 6964865 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 129 | 411 | 0 |
| EKMFKIYVYEEGDPPIFHYGLCKDIYSMEGLFLNFMENDILNYRTRDPDRAHVYFLPFSVVMILHHLFDPVVRDKAVLERVIVDYVRIISNKYPYWNTSD GFDHFMLSCHDWGHRATWYVKKLFFNSIRVLCNANISEYFNPEKDAPFPEINLPTGEINNLTGGLDPISRTTLAFFAGKSHGKIRPVLLNHWKEKDKDIL VYENLPDGLDYKDLMRRSRFCICPSGHEVASPRIPEAIYSECVPVLISENYVLPFSDVLNWEKFSVSVSVKEIPELKRILMDI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 460 Download |
| MRDYIPKYLN AFLLAFATSA VVFAIFIAKG SKTSSHLYFT TSSSLWTSSF SSSFITEKRK 60 RNGSNPGSVS WKRDGKVEAE LATARALIRE AQLNPNSTTS SPLRDEDYVP HGDIYRNPYA 120 FHRSYLLMEK MFKIYVYEEG DPPIFHYGLC KDIYSMEGLF LNFMENDILN YRTRDPDRAH 180 VYFLPFSVVM ILHHLFDPVV RDKAVLERVI VDYVRIISNK YPYWNTSDGF DHFMLSCHDW 240 GHRATWYVKK LFFNSIRVLC NANISEYFNP EKDAPFPEIN LPTGEINNLT GGLDPISRTT 300 LAFFAGKSHG KIRPVLLNHW KEKDKDILVY ENLPDGLDYK DLMRRSRFCI CPSGHEVASP 360 RIPEAIYSEC VPVLISENYV LPFSDVLNWE KFSVSVSVKE IPELKRILMD IPEDRYIRLH 420 EGVKKVKRHI LVNDPPKRYD VFNMIIHSIW LRRLNVKLL* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-65 | 128 | 411 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI28482.1 | 0 | 62 | 458 | 235 | 634 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_187419.1 | 0 | 1 | 459 | 1 | 470 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002264111.1 | 0 | 128 | 458 | 1 | 330 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002320537.1 | 0 | 67 | 458 | 4 | 393 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524592.1 | 0 | 76 | 459 | 6 | 387 | catalytic, putative [Ricinus communis] |
