| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10024789m |
| Family | AA7 |
| Protein Properties | Length: 569 Molecular Weight: 62967.5 Isoelectric Point: 10.2047 |
| Chromosome | Chromosome/Scaffold: 1 Start: 8334483 End: 8336885 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 73 | 531 | 0 |
| NARFNTSSTRKPTIIVTPRSDSHVSAAVICSKPLKNFVLKIRSGGHDYDGLSYISDKPFFILDLSNLRDVSVDIASNSAWISAGATLGEVYYRIWEKSKI HGFPAGVCPTVGVGGHLSGGGYGNMLRKFGLSVDNLIDAKIVDVKGRILDRKSMGEDLFWAISGGGGGSFGVVLGYKVKLVPVPPIVTVFRVEQYMDSGA VDMVHKWQSVGPKTDPNLFMRMLIQPVTRKKVKTVRASVVALFLGRANDVVSLLRKEFPELALKKENCTEMSWLQSALWWDNHVNATQTDPKVFLDRNLD SASFGKRKSDYVATPIPRNGIESLFKKMIELGKIGLVFNPYGGKMAEIAEDATPFPHRKKLFKIQYSVNWKESSPEIEKGFLNQAKVLHSFMTGFVSKSP RSAYLNYRDVDIGVNDHGKNSYKEGEVYGRSYFGKNFDRLVKVKTAVDPGNFFRNEQSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 569 Download |
| MLTTRQTFCS VVFFLLFLSL PLCSFSQSPN SVYNSFLKCF SEKTKSPQAQ IAKNVFSQSD 60 PSYSSVLRAY IRNARFNTSS TRKPTIIVTP RSDSHVSAAV ICSKPLKNFV LKIRSGGHDY 120 DGLSYISDKP FFILDLSNLR DVSVDIASNS AWISAGATLG EVYYRIWEKS KIHGFPAGVC 180 PTVGVGGHLS GGGYGNMLRK FGLSVDNLID AKIVDVKGRI LDRKSMGEDL FWAISGGGGG 240 SFGVVLGYKV KLVPVPPIVT VFRVEQYMDS GAVDMVHKWQ SVGPKTDPNL FMRMLIQPVT 300 RKKVKTVRAS VVALFLGRAN DVVSLLRKEF PELALKKENC TEMSWLQSAL WWDNHVNATQ 360 TDPKVFLDRN LDSASFGKRK SDYVATPIPR NGIESLFKKM IELGKIGLVF NPYGGKMAEI 420 AEDATPFPHR KKLFKIQYSV NWKESSPEIE KGFLNQAKVL HSFMTGFVSK SPRSAYLNYR 480 DVDIGVNDHG KNSYKEGEVY GRSYFGKNFD RLVKVKTAVD PGNFFRNEQS IPTLPIANGT 540 VVTESGTARR WSRAGGATVV ATVALHVF* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0277 | GlcD | 6.0e-8 | 65 | 534 | 505 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam01565 | FAD_binding_4 | 3.0e-16 | 84 | 222 | 141 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| pfam08031 | BBE | 3.0e-17 | 475 | 532 | 58 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD94511.1 | 0 | 29 | 535 | 15 | 526 | hypothetical protein [Arabidopsis thaliana] |
| RefSeq | NP_172642.3 | 0 | 6 | 535 | 2 | 530 | FAD binding / catalytic/ electron carrier/ oxidoreductase [Arabidopsis thaliana] |
| RefSeq | NP_193815.2 | 0 | 30 | 568 | 33 | 570 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_193816.1 | 0 | 32 | 534 | 34 | 535 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_974580.1 | 0 | 30 | 534 | 33 | 536 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 35 | 535 | 6 | 514 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 30 | 534 | 7 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 30 | 534 | 7 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_B | 0 | 29 | 534 | 4 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_A | 0 | 29 | 534 | 4 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
