y
Basic Information | |
---|---|
Species | Thellungiella halophila |
Cazyme ID | Thhalv10024793m |
Family | GT47 |
Protein Properties | Length: 567 Molecular Weight: 65011.6 Isoelectric Point: 7.4547 |
Chromosome | Chromosome/Scaffold: 1 Start: 3063113 End: 3065304 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 237 | 520 | 0 |
EKKLKVYVYREGKRPVLHKPVLKGIYASEGWFMKQLKASKTFVTKDPSKAHLFYLPFSSKMLEETLYVPGSHSDRNLIEFLKNYLDMISSKYPFWNRTGG SDHFLVACHDWAPSETRQYMANCIRALCNSDVSEGFVFGKDVALPETTILVPRRPLRALGGKPSSQRQILAFFAGGMHGYLRPRLLQNWGGNRDPDMKIF SEIPKSKGKKSYMEYMKSSKYCICPKGHEVNSPRVVEALFYECVPVIISDNFVPPFFEVLNWESFAVFVLERDVPDLKNILVSI |
Full Sequence |
---|
Protein Sequence Length: 567 Download |
MKLLRVAGVV FIFIVTFQFV NIHYFGGAIF SLPSEDKFPI SSINGSTEPI RPLSGTEKLN 60 FSSSRSVEVA KEERTGLEED HIIGSDKSES IESHDSFIED AEDKETLELL LRTGSSSNGS 120 YSDIVEDADI VNENSRNVEI LESKSDTSVD NLSPEVKRLM NVSNSGVVPI TEMMNLLHQS 180 RTSHVSLKLK RSSAVDTELL FARTQIENPP MVENDPLLHG PLYWNLSMFK RSYELMEKKL 240 KVYVYREGKR PVLHKPVLKG IYASEGWFMK QLKASKTFVT KDPSKAHLFY LPFSSKMLEE 300 TLYVPGSHSD RNLIEFLKNY LDMISSKYPF WNRTGGSDHF LVACHDWAPS ETRQYMANCI 360 RALCNSDVSE GFVFGKDVAL PETTILVPRR PLRALGGKPS SQRQILAFFA GGMHGYLRPR 420 LLQNWGGNRD PDMKIFSEIP KSKGKKSYME YMKSSKYCIC PKGHEVNSPR VVEALFYECV 480 PVIISDNFVP PFFEVLNWES FAVFVLERDV PDLKNILVSI TEDRYREMQM RVKMVQKHFL 540 WHSRPERFDI FYMILHSIWY NRVFQT* 600 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-72 | 236 | 520 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 1 | 565 | 29 | 592 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_197954.1 | 0 | 154 | 565 | 236 | 651 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 122 | 565 | 222 | 665 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 154 | 565 | 55 | 467 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 173 | 566 | 1 | 395 | predicted protein [Populus trichocarpa] |