| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10025280m |
| Family | GT47 |
| Protein Properties | Length: 428 Molecular Weight: 48941.8 Isoelectric Point: 8.4284 |
| Chromosome | Chromosome/Scaffold: 1 Start: 758898 End: 761038 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 103 | 380 | 0 |
| ERRFKVYIYPDGDPNTFYQTPRKVTGKYASEGYFFQNIRESRFRTLDPEEADLFFIPVSCHKMRGKGTSYENMTVIVQNYVDGLIAKYPYWNRTLGADHF FVTCHDVGVRAFEGSPLLIKNTIRVVCSPSYNVGFIPHKDVALPQVLQPFALPAGGNDVENRTTLGFWAGHRNSKIRVILARVWENDTELDISNNRINRA TGHLVYQKRFYRTKFCICPGGSQVNSARITDSIHYGCIPVILSDYYDLPFNDILNWRKFAVVLRERDVYNLKQILKNI | |||
| Full Sequence |
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| Protein Sequence Length: 428 Download |
| MTIVKPSQLA SSGGSSPLCS LKGSLLTVAV LTFVSLFYLS LNSLRNSPPS PVVVGPIQVP 60 QTFVKEDTLD NSDNDGAPAE EEENYSDVYH SPESFRLNYA EMERRFKVYI YPDGDPNTFY 120 QTPRKVTGKY ASEGYFFQNI RESRFRTLDP EEADLFFIPV SCHKMRGKGT SYENMTVIVQ 180 NYVDGLIAKY PYWNRTLGAD HFFVTCHDVG VRAFEGSPLL IKNTIRVVCS PSYNVGFIPH 240 KDVALPQVLQ PFALPAGGND VENRTTLGFW AGHRNSKIRV ILARVWENDT ELDISNNRIN 300 RATGHLVYQK RFYRTKFCIC PGGSQVNSAR ITDSIHYGCI PVILSDYYDL PFNDILNWRK 360 FAVVLRERDV YNLKQILKNI PHSEFVSLHN NLVKVQKHFQ WNSPPVKFDA FHMIMYELWL 420 RHHVIKY* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-61 | 102 | 380 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAH56870.1 | 0 | 1 | 397 | 1 | 395 | AT4G38040 [Arabidopsis thaliana] |
| RefSeq | NP_195517.1 | 0 | 1 | 427 | 1 | 425 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002266299.1 | 0 | 1 | 427 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002268836.1 | 0 | 18 | 427 | 12 | 417 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002307304.1 | 0 | 18 | 427 | 1 | 406 | predicted protein [Populus trichocarpa] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EG459159 | 264 | 165 | 428 | 0 |
| FY454337 | 315 | 22 | 336 | 0 |
| EH770778 | 275 | 118 | 392 | 0 |
| JG847451 | 280 | 76 | 351 | 0 |
| GO268625 | 269 | 102 | 370 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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