| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10027426m |
| Family | AA7 |
| Protein Properties | Length: 539 Molecular Weight: 59834.4 Isoelectric Point: 8.754 |
| Chromosome | Chromosome/Scaffold: 1 Start: 8331867 End: 8333483 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 74 | 531 | 0 |
| NARFNTSSTPKPTIIVTPRSDSHVSAAVICSKPLNFVLKIRSGGHDYDGLSYISDKPFFILDMSNLREVSVDIADQSAWISAGATLGEVYYRIWEKSKIH GFPAGVCPTVGVGGHLSGGGYGNMVRKFGLSVDYVEDAKIVDVKGQILDRKSMGEDLFWAICGGGGASFGVVLGYKVKLVPVPDTVTVFRVEQYMDTGAV DMVHKWQSVGPKTDPNLFMRMLIQPVTRKKVKTVRASVVALFLGKADDVVSLLAKDFQELGLKKENCTEMTWIQSALWWDNDENATQTDPKVLLDRNLDS ASFGKRKSDYVEAEIPRDGIESLFKKMIELGKIGLVFNPYGGKMAEVAVDATPFPHRKKLFKIQYSVNWKESSPEIEKGFLDQAKVLYSFMTGFVSKNPR NAYLNYRDVDIGVNDHGVNSYEEGEVYGRKYFGANFDRLVKVKTAVDPENFFRNEQSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 539 Download |
| MITTQTFVSV LFSVLFLSPP FSSFAAPPSS DSVYESFVQC FSDKTKSPQT QITQKVFSQT 60 NPSYSSVLRA YIRNARFNTS STPKPTIIVT PRSDSHVSAA VICSKPLNFV LKIRSGGHDY 120 DGLSYISDKP FFILDMSNLR EVSVDIADQS AWISAGATLG EVYYRIWEKS KIHGFPAGVC 180 PTVGVGGHLS GGGYGNMVRK FGLSVDYVED AKIVDVKGQI LDRKSMGEDL FWAICGGGGA 240 SFGVVLGYKV KLVPVPDTVT VFRVEQYMDT GAVDMVHKWQ SVGPKTDPNL FMRMLIQPVT 300 RKKVKTVRAS VVALFLGKAD DVVSLLAKDF QELGLKKENC TEMTWIQSAL WWDNDENATQ 360 TDPKVLLDRN LDSASFGKRK SDYVEAEIPR DGIESLFKKM IELGKIGLVF NPYGGKMAEV 420 AVDATPFPHR KKLFKIQYSV NWKESSPEIE KGFLDQAKVL YSFMTGFVSK NPRNAYLNYR 480 DVDIGVNDHG VNSYEEGEVY GRKYFGANFD RLVKVKTAVD PENFFRNEQS IPTLPSKA* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0277 | GlcD | 3.0e-10 | 66 | 534 | 500 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam01565 | FAD_binding_4 | 4.0e-17 | 85 | 222 | 139 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| pfam08031 | BBE | 2.0e-18 | 475 | 532 | 58 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_171700.1 | 0 | 25 | 537 | 20 | 537 | ATSEC1A; FAD binding / catalytic/ electron carrier/ oxidoreductase [Arabidopsis thaliana] |
| RefSeq | NP_172642.3 | 0 | 14 | 537 | 7 | 532 | FAD binding / catalytic/ electron carrier/ oxidoreductase [Arabidopsis thaliana] |
| RefSeq | NP_193815.2 | 0 | 30 | 534 | 32 | 536 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_193816.1 | 0 | 20 | 538 | 21 | 539 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_974580.1 | 0 | 30 | 538 | 32 | 540 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 35 | 535 | 5 | 514 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 25 | 534 | 1 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 25 | 534 | 1 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_B | 0 | 27 | 537 | 4 | 499 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_A | 0 | 27 | 537 | 4 | 499 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
