| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10027719m |
| Family | GT47 |
| Protein Properties | Length: 529 Molecular Weight: 60355.1 Isoelectric Point: 9.6069 |
| Chromosome | Chromosome/Scaffold: 14 Start: 8524083 End: 8526663 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 218 | 500 | 0 |
| ERKLKVYVYKEGKKPIFHKPMPRGIYASEGWFMKLMESNKKFVVKDPRKAHLFYIPVSIKALRTSLGRDFQTPTSLADHLKEYVDLIAGKYKFWNRTGGA DHFLVACHDWGNKLTKKHMKNSVRALCNSNVAQGFRIGIDTALPVTYIRSAESPLEYLGGKTPSERKILAFFAGSMHGYLRPILLQLWENKEPDMKILGP MPRDPQSKKQYREYMKSSRYCICARGYEVHTPRVVEAIMNECVPVIIADNYVPPFFEVLEWEEFAVFVKEKDIANLRNILLSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 529 Download |
| MRIVNRLERF QYSDIRRLLS GIIVVTVGFV VLLVLCFGLP CRNASCLSLV KVSGFVDSQV 60 SLVKTEMKYI NVSTDVDVDE DEKGKRKKDY SLDIDREDDD VAISKVKVEL NVSLEKPKMA 120 VESSVLVSGK DSREGNVLSI IRHKQEAAVS IAQMNTLLIQ SLSSFQSPKP RWSSVRDSEM 180 LAAKTEIENA SGVDGFIGLD ASVYRNISKF QRSYDLMERK LKVYVYKEGK KPIFHKPMPR 240 GIYASEGWFM KLMESNKKFV VKDPRKAHLF YIPVSIKALR TSLGRDFQTP TSLADHLKEY 300 VDLIAGKYKF WNRTGGADHF LVACHDWGNK LTKKHMKNSV RALCNSNVAQ GFRIGIDTAL 360 PVTYIRSAES PLEYLGGKTP SERKILAFFA GSMHGYLRPI LLQLWENKEP DMKILGPMPR 420 DPQSKKQYRE YMKSSRYCIC ARGYEVHTPR VVEAIMNECV PVIIADNYVP PFFEVLEWEE 480 FAVFVKEKDI ANLRNILLSI PEERYVGMQA RVNMVQQHFL WHKKPPDI* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0438 | RfaG | 0.002 | 198 | 523 | 343 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
| pfam03016 | Exostosin | 2.0e-65 | 217 | 500 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB08970.1 | 0 | 1 | 525 | 1 | 535 | unnamed protein product [Arabidopsis thaliana] |
| EMBL | CAN76867.1 | 0 | 83 | 525 | 202 | 689 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI28021.1 | 0 | 83 | 525 | 202 | 641 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_198516.1 | 0 | 1 | 526 | 1 | 545 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002280595.1 | 0 | 83 | 525 | 200 | 639 | PREDICTED: hypothetical protein [Vitis vinifera] |
