| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10028137m |
| Family | GT47 |
| Protein Properties | Length: 526 Molecular Weight: 60981.1 Isoelectric Point: 10.0102 |
| Chromosome | Chromosome/Scaffold: 14 Start: 2813268 End: 2814846 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 142 | 461 | 0 |
| SCEGKGVYVYDLPSKFNRDLLVDCVDMVPWTNMCKFFKNEGFGEAIKNLGHGWFRTHQYALEPILHSRFLKHPCRVYKESQAKIFYVPFYGGFDVLRWHF KNVSDDVKDRLGIEVLKWLRSKKSWNSNAGKDHVFVLGKISWDFRRSKLPWGSRFLELQEMQKPTKLLIEKHPWEYIAIPHPTYFHPKTDHDIISWQIKM TRKTRRNLISFAGGARPGNPNSIRSTLIQQCTSFSDQCRFLNCSNGSCNKPENVIKLFRDSEFCLQPSGDSPTRKSVFDSLISGCIPVFFNPYTAYYQYT WHLPEDHKRYSVYINEEDVK | |||
| Full Sequence |
|---|
| Protein Sequence Length: 526 Download |
| MATLVSKRKP TTPKKTEDSK ILYIPLTISL FFVLYLLFSS SIIICSRKVK GSSSVLNKDG 60 EMDSQKNDTL TGETAGDKVS SEVAKRYGVN HKSSKNESEE EQYKYIKPKS KGEEYALKAV 120 IKYLHVQRSW ISTRAKSKKS RSCEGKGVYV YDLPSKFNRD LLVDCVDMVP WTNMCKFFKN 180 EGFGEAIKNL GHGWFRTHQY ALEPILHSRF LKHPCRVYKE SQAKIFYVPF YGGFDVLRWH 240 FKNVSDDVKD RLGIEVLKWL RSKKSWNSNA GKDHVFVLGK ISWDFRRSKL PWGSRFLELQ 300 EMQKPTKLLI EKHPWEYIAI PHPTYFHPKT DHDIISWQIK MTRKTRRNLI SFAGGARPGN 360 PNSIRSTLIQ QCTSFSDQCR FLNCSNGSCN KPENVIKLFR DSEFCLQPSG DSPTRKSVFD 420 SLISGCIPVF FNPYTAYYQY TWHLPEDHKR YSVYINEEDV KGKRVNVVEK LMAKTPRERE 480 DMRSYIVHQL LPGLVYGDSN AKFKKFRDAF DITFDNLLEK INKSV* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-70 | 142 | 473 | 347 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_176534.2 | 0 | 65 | 525 | 179 | 664 | catalytic [Arabidopsis thaliana] |
| RefSeq | NP_198941.1 | 0 | 4 | 525 | 1 | 560 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002269913.1 | 0 | 114 | 523 | 127 | 536 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002299537.1 | 0 | 109 | 523 | 155 | 571 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509789.1 | 0 | 114 | 523 | 157 | 565 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
