| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10028139m |
| Family | GT47 |
| Protein Properties | Length: 221 Molecular Weight: 25679.6 Isoelectric Point: 8.5728 |
| Chromosome | Chromosome/Scaffold: 14 Start: 8467217 End: 8468504 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 90 | 196 | 1.3e-34 |
| HGYLRPILLQLWENKEPDMKILGPMPRDPQSKKQYREYMKSSRYCICARAYEVHTPRVVEAIMNECVPVMKSTLLVPPFFEVLEWEEFAVFVKEKDIPKL RNILLSI | |||
| Full Sequence |
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| Protein Sequence Length: 221 Download |
| EGKKPIFHKP KPRGIYASEE KAHLFYIPVS IKALRTSLGR DFQTPKSLAD HLEEYVDLIA 60 GKYKFWNRTG GADHFLVACH DWNRDQYSMH GYLRPILLQL WENKEPDMKI LGPMPRDPQS 120 KKQYREYMKS SRYCICARAY EVHTPRVVEA IMNECVPVMK STLLVPPFFE VLEWEEFAVF 180 VKEKDIPKLR NILLSIRWDA SKGKNGATTF PVEQETSETE * 240 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-10 | 5 | 82 | 80 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 3.0e-24 | 85 | 196 | 112 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB08970.1 | 4.99997e-41 | 1 | 82 | 233 | 332 | unnamed protein product [Arabidopsis thaliana] |
| DDBJ | BAB08970.1 | 0 | 88 | 203 | 397 | 517 | unnamed protein product [Arabidopsis thaliana] |
| RefSeq | NP_198516.1 | 4.00001e-41 | 1 | 82 | 247 | 346 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_198516.1 | 0 | 88 | 203 | 411 | 526 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002324437.1 | 0 | 1 | 196 | 12 | 285 | predicted protein [Populus trichocarpa] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EX024527 | 109 | 88 | 196 | 0 |
| EX029147 | 109 | 88 | 196 | 0 |
| EV214558 | 109 | 88 | 196 | 0 |
| EV549582 | 109 | 88 | 196 | 0 |
| EV549582 | 21 | 196 | 216 | 6.5 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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