y
Basic Information | |
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Species | Volvox carteri |
Cazyme ID | Vocar20000433m |
Family | GT47 |
Protein Properties | Length: 924 Molecular Weight: 102161 Isoelectric Point: 8.7803 |
Chromosome | Chromosome/Scaffold: 17 Start: 2018595 End: 2032881 |
Description | exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 579 | 763 | 4.1e-37 |
SFLPFPPPPLLLLRRTTSYTSCRTYTRTYRIWQDLVIPAFKRSEHFRSSPYVGAAPSERNVFLFFRGDLRLAPGQDPECKYSRCIRQTLYNLSISERWRE KYNVLLGDTSTVHGDYSVLLSQSLFCLVAPGDGWSPRLEDAVLHGCIPVIIMDEVQAVFESILDLPSFSVRIPQANMTQIVTILK |
Full Sequence |
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Protein Sequence Length: 924 Download |
MARSQEATRL LVLLAVAVLP PGLAVFNSEE LLPYAELDES AAQFRRTLLQ VSGSAGAAGS 60 AAGGEAGGGG DAATSPRVPP LPQTPEEHCA VTRGSWCGHY YRQPLVPQQQ QQQQRTWRRS 120 WPQIPTPRPP PKRGDKPCPN DCSGVGQCQY DFGICYCPAG YGGADCSQPR KRPCWRMGPD 180 KRDLGWHNYT EWSHSRCAGI CDDDIAMCYC PPETKYGRIE APPGSPLGTP PVRAGRPLYW 240 CQPSTCGALP PPPNALQPHP PTPPSAKSLQ QPYRCGGGRG STTMRHLLCG TTATSLILKA 300 VRPAAERGSN VRPCPPDKSL MLSHASPRQC FLVCVYVHVH VRQQQDEQGN KVLWGAVTYE 360 NLFGREGWCN GDVPSFMCPC RNGGVGEGDE RIDGRVGTLC NIIVEQFCVN QCSGRGECDQ 420 GFCRCHAGWY GHDCSRRRAG LPVDTPQIHG VCDRGVRHVE RGVALRDGLG VGRRNRLFLV 480 GGARNNGCRT DAYAYVNESA FVYTSFGDIG MGGVAHAIVN THTATHAPTH TYIHIYKYTH 540 MHYIYCIYIQ YIQLYTHTSG HKLNILALFP PAPGPLPRSF LPFPPPPLLL LRRTTSYTSC 600 RTYTRTYRIW QDLVIPAFKR SEHFRSSPYV GAAPSERNVF LFFRGDLRLA PGQDPECKYS 660 RCIRQTLYNL SISERWREKY NVLLGDTSTV HGDYSVLLSQ SLFCLVAPGD GWSPRLEDAV 720 LHGCIPVIIM DEVQAVFESI LDLPSFSVRI PQANMTQIVT ILKGRSSHKK KRDHAQARSP 780 LQGPGIVRTL QPRSGTREEI GFFPALAIPA GRVKAMQENL AKVWFRYRYL GVKMAQRDAV 840 EVVNRHREMY GGQLRPNPGV QYATSHVDDA FSTLMQWLYA RIPEVHGGGA GLSEFSRDQA 900 SWKLCEIRWG FAATTTAVSS AKI* 960 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-18 | 610 | 763 | 155 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001698039.1 | 5e-23 | 89 | 245 | 113 | 265 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001698039.1 | 0.000001 | 401 | 449 | 294 | 342 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001698039.1 | 0 | 611 | 887 | 574 | 810 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001700890.1 | 8e-20 | 119 | 238 | 4 | 137 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001700890.1 | 0 | 611 | 887 | 466 | 704 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |