| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20000485m |
| Family | GT47 |
| Protein Properties | Length: 1213 Molecular Weight: 134404 Isoelectric Point: 7.9261 |
| Chromosome | Chromosome/Scaffold: 17 Start: 1988955 End: 1999090 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 487 | 914 | 3.99931e-42 |
| TIHYSLLEAEFTASLLGSFEAGNASVWVGYNAYSTEPVLHELFLTSEHRTLDPEEADYFYVPVSVGCLFDVYGWNEIPRWPQGMLAAAYGMTVPGEVTRP THACIASICTVHAVQKMMNDAFSAHNTNLAGPRTHGAAMMQREAMKWLNATFPWFARRGGRDHIWFNPHDEGACYTWKDIWPGVMLSHWGRTDFPHASNT AYSQSIIDLSDSSSGPMKSYSGFHGGGGGEMDHGCNVRPSTVRQDNYSLPLHHAVHPGNWLDQTSKTHPCFDPRKVDIANLDALNVRNAKQDLVIPAFKQ PAHYKDSPYMGTANPVNRDIFAFFMGDLRMEPGRDPACRYSSSSNPCCPIFRRCIRQRIYNLSQEHHWKEAYGIWYGDRKDMAATAGYSQLLARSIFCFV LPGDGWSPRLEDAVLHGCIPVIIMDEVQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1213 Download |
| MEVNRSSLNP LPELAEQRCF LTRGSWCIKF FLQEPTPRHP PKYHNKSCPG NCAGVGVCNA 60 EYGICYCPAG YGGEDCSQPR KRPCKHMGPD KRDAGWHNLT AWSHTRCAGI CDDDIAMCYC 120 PPETKYGRIE APPGSPLGTP PVRAGRPLFM CSPGELSSSR PTTSATALTS IPSLLPVAAA 180 AAAAHLPYCG GEMNRSCGGE MNSCCCSYCV ILQYACGLCL LGRIRSAKVW ALTGRTGCPP 240 QDAEGRKVEW GGTPYQDLFG PEGWCNADKP KFKCPCRLDG LGGSTCSEVR EQVCINQCSG 300 HGECQQGFCK CYDGWYGTDC GRRRAGTNPE EAPKELYSLS FVRRVWWAWI SDVVTHVVAT 360 EDPPLTPVRR RPYIYVYDVK PEYGTDIIQY RIEGSHCVYR LPPSDGVCEG GRRSVARLGI 420 EGHVVELTLL KGSLVNQREL LRKKPARDTK GGAGSSFGGV MGPYAGPVLG LVVPLKQLLT 480 HLVCRRTIHY SLLEAEFTAS LLGSFEAGNA SVWVGYNAYS TEPVLHELFL TSEHRTLDPE 540 EADYFYVPVS VGCLFDVYGW NEIPRWPQGM LAAAYGMTVP GEVTRPTHAC IASICTVHAV 600 QKMMNDAFSA HNTNLAGPRT HGAAMMQREA MKWLNATFPW FARRGGRDHI WFNPHDEGAC 660 YTWKDIWPGV MLSHWGRTDF PHASNTAYSQ SIIDLSDSSS GPMKSYSGFH GGGGGEMDHG 720 CNVRPSTVRQ DNYSLPLHHA VHPGNWLDQT SKTHPCFDPR KVDIANLDAL NVRNAKQDLV 780 IPAFKQPAHY KDSPYMGTAN PVNRDIFAFF MGDLRMEPGR DPACRYSSSS NPCCPIFRRC 840 IRQRIYNLSQ EHHWKEAYGI WYGDRKDMAA TAGYSQLLAR SIFCFVLPGD GWSPRLEDAV 900 LHGCIPVIIM DEVQRIIVRS TLARCVLTYR YMYDLDRYMY VVFQSILDVG QISVHIAEGE 960 IDRIVEILQA VSPELIETMQ YNINKVWHRF RYLGIRMAML DARRRLERYM EEHGGEAPKN 1020 PGSEYSVSRQ DDAFDTIIQW LYDRMPYVHG VAKRRRSLNA VAVGDVLMVM MVAVTMVMMV 1080 LFLWFRSLRF YGGNGGLWLR KGKGKGVPGG DMITPVTYTD HITHEEAPGH DVGRVLGGGK 1140 VVIIPTGHQL IHLPDRGIAF GCMYVSSEQL AKPGCAVLIC RYDGLRDGGG ASHNSRRSRS 1200 GSGSGIAGQP AA* 1260 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.004 | 296 | 320 | 27 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 0.0006 | 626 | 674 | 49 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 2.0e-6 | 513 | 555 | 43 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 9.0e-14 | 736 | 971 | 239 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001698039.1 | 4e-25 | 12 | 230 | 105 | 322 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698039.1 | 0 | 463 | 1050 | 347 | 810 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001700890.1 | 1e-22 | 32 | 171 | 9 | 162 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001700890.1 | 6e-17 | 251 | 400 | 155 | 295 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001700890.1 | 0 | 479 | 1050 | 274 | 704 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
