| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20000681m |
| Family | CE1 |
| Protein Properties | Length: 291 Molecular Weight: 32072 Isoelectric Point: 5.8415 |
| Chromosome | Chromosome/Scaffold: 19 Start: 2139950 End: 2143178 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE1 | 25 | 283 | 0 |
| STVLGCDMTFTVYFPPAAETGKVPVLYYLSGLTCNDENFIQKSGAQRAAATRGIALVAPDTSPRGLGVEGEADSWDFGVGAGFYLNSTQEKWRAWRMYDY VVEELPSLLRSTAPFATSLDVDQASVFGHSMGGHGALVVGLRNPQTYRSISAFAPVCHPINCPWGVKAFTGYLGEDRELWKQYDACELLRSFSGPVRPPI LVDTGSADKFLQVQLQPQALEAAIQETGYSPATMRTQEGYDHSYFFISTFVDDHINFHA | |||
| Full Sequence |
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| Protein Sequence Length: 291 Download |
| MATAVEEISA NRHYNGYNRR YKHRSTVLGC DMTFTVYFPP AAETGKVPVL YYLSGLTCND 60 ENFIQKSGAQ RAAATRGIAL VAPDTSPRGL GVEGEADSWD FGVGAGFYLN STQEKWRAWR 120 MYDYVVEELP SLLRSTAPFA TSLDVDQASV FGHSMGGHGA LVVGLRNPQT YRSISAFAPV 180 CHPINCPWGV KAFTGYLGED RELWKQYDAC ELLRSFSGPV RPPILVDTGS ADKFLQVQLQ 240 PQALEAAIQE TGYSPATMRT QEGYDHSYFF ISTFVDDHIN FHADVLLPGK * 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam12697 | Abhydrolase_6 | 9.0e-5 | 139 | 270 | 136 | + Alpha/beta hydrolase family. This family contains alpha/beta hydrolase enzymes of diverse specificity. | ||
| pfam00756 | Esterase | 2.0e-46 | 25 | 281 | 267 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 5.0e-75 | 1 | 286 | 314 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 2.0e-129 | 6 | 286 | 282 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 0 | 1 | 288 | 288 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0018738 | S-formylglutathione hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABK22177.1 | 0 | 7 | 286 | 6 | 280 | unknown [Picea sitchensis] |
| GenBank | ACJ11734.1 | 0 | 1 | 286 | 1 | 282 | S-formylglutathione hydrolase [Gossypium hirsutum] |
| RefSeq | NP_181684.1 | 0 | 1 | 286 | 1 | 282 | SFGH (S-FORMYLGLUTATHIONE HYDROLASE); S-formylglutathione hydrolase/ hydrolase, acting on ester bonds [Arabidopsis thaliana] |
| RefSeq | XP_001697508.1 | 0 | 1 | 286 | 1 | 286 | esterase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001763419.1 | 0 | 8 | 286 | 1 | 275 | predicted protein [Physcomitrella patens subsp. patens] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3s8y_A | 0 | 4 | 286 | 3 | 278 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 4 | 286 | 3 | 278 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 4 | 286 | 3 | 278 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3fcx_B | 0 | 4 | 286 | 2 | 280 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 4 | 286 | 2 | 280 | A Chain A, Crystal Structure Of Human Esterase D |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
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| Hit | Length | Start | End | EValue |
| CV287891 | 284 | 1 | 284 | 0 |
| DV157903 | 287 | 1 | 286 | 0 |
| HO435793 | 284 | 4 | 286 | 0 |
| DV157508 | 287 | 1 | 286 | 0 |
| HO352974 | 285 | 3 | 286 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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