| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20000771m |
| Family | GT47 |
| Protein Properties | Length: 750 Molecular Weight: 83807.6 Isoelectric Point: 7.6657 |
| Chromosome | Chromosome/Scaffold: 19 Start: 764661 End: 773896 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 269 | 622 | 0 |
| RRPLIYVYDLEPLYQSKLLQYRVSPTWCVHRLHRWPDNGTQWTDVWVYAADTLLHESLLISEHRTFDPEEADFFYVPHYASCLPFPIGVWADAPWFPEPG GPRVKQMVNMVRDTLDWINSTFPYWRRRGGRDHIWLFTHDEGACWAPTAINASIWLTHWGRTELNHTSNTAFLADKYDSDFAGPLQPEGFVKYIKGHPCF NPEKDLVIPAFKAPSHYHASPLQGNPARERDLLFFFRGDVGKNRLPNYSRGVRQQIYKMAKEGGWAEKYRFYIGDGSDVEGDYSEMLSRAIFCLVAPGDG WSARMEDAVLHGCIPVVIADGVEAVFENVLELDAFALRLPQEAVPRLLDVLRAV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 750 Download |
| WTTKSQSIQG YASKQRCAYT RGTWCTNFFA QELVPWRPAP RGDMDCPGGC NNVGRCNYDT 60 GKCDCPAGDP FERRSEPYSH IGPDKRDLDL GTRNVHFLYG RCGGVCDDDT AICYCDGPMG 120 RVPAPPDAPP GTPPIRVGRP LITMHHAPKT TWNGSWAFGE VPYDNVYGPQ GYCNVTDPIW 180 VPGCGMDGWG GRTCDQPVEA FCPGACSGHG QCYLGWCICD AGYYGHDCAR RRAGLSPLPS 240 GIRQKRWLEG VVGSEPPAAM EPPPRAERRR PLIYVYDLEP LYQSKLLQYR VSPTWCVHRL 300 HRWPDNGTQW TDVWVYAADT LLHESLLISE HRTFDPEEAD FFYVPHYASC LPFPIGVWAD 360 APWFPEPGGP RVKQMVNMVR DTLDWINSTF PYWRRRGGRD HIWLFTHDEG ACWAPTAINA 420 SIWLTHWGRT ELNHTSNTAF LADKYDSDFA GPLQPEGFVK YIKGHPCFNP EKDLVIPAFK 480 APSHYHASPL QGNPARERDL LFFFRGDVGK NRLPNYSRGV RQQIYKMAKE GGWAEKYRFY 540 IGDGSDVEGD YSEMLSRAIF CLVAPGDGWS ARMEDAVLHG CIPVVIADGV EAVFENVLEL 600 DAFALRLPQE AVPRLLDVLR AVPQRAIRSK QAHLGRVWQR YRWASLPKLV SELRSAQQRN 660 QVAAGHSTED DEGGTAAATA AAGAGGVASR RQRRRRGLMT EGHSTAGAGS GVGVPRRFPL 720 PRPYRGDPAQ DDAFATIMQW LHSRIPHTR* 780 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-49 | 273 | 622 | 351 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001691329.1 | 0 | 14 | 749 | 81 | 815 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693194.1 | 0 | 34 | 749 | 7 | 661 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001697525.1 | 0 | 68 | 640 | 5 | 593 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698117.1 | 0 | 12 | 749 | 72 | 800 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001700890.1 | 0 | 34 | 749 | 13 | 703 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD801053 | 291 | 215 | 503 | 0 |
| FD867786 | 240 | 371 | 607 | 0 |
| HO651219 | 409 | 272 | 664 | 0 |
| GE255396 | 253 | 395 | 644 | 0 |
| FD814505 | 223 | 363 | 580 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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