| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20001320m |
| Family | GT4 |
| Protein Properties | Length: 517 Molecular Weight: 56941.6 Isoelectric Point: 8.2688 |
| Chromosome | Chromosome/Scaffold: 24 Start: 1158618 End: 1165651 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT4 | 206 | 326 | 6.8e-29 |
| RDEIVLVVLCRLVYRKGVDLLSLVLPAVCSRHANVRVLVGGDGPKRLLLEKVISDHGLEERVVLEGAVPHERARDFMVRGHVFVNASLTEAFCMALVEAA AAGLVVVSTAVGGVPEVLPPD | |||
| Full Sequence |
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| Protein Sequence Length: 517 Download |
| METGGGQRQH RVVMVSDFFY PNFGGVENHI YQLSQCLINL GHKVVVVTHA YGNCTGVRYL 60 TNGLKVYYLP RLPFYQQATF PTLMGWARLL RVICVREGAT LVHGHQAFST MALEACINAR 120 SLGLRVVFTD HSLFGFADPG SIVLNKVLKA VLSDVHAVIC VSHTSKENTV LRACLPPSSV 180 SVIPNAVDAS QFQPNPRAIW PSNPVRDEIV LVVLCRLVYR KGVDLLSLVL PAVCSRHANV 240 RVLVGGDGPK RLLLEKVISD HGLEERVVLE GAVPHERARD FMVRGHVFVN ASLTEAFCMA 300 LVEAAAAGLV VVSTAVGGVP EVLPPDMIEL AEPTAEGLLA AIERALLRVP HQRPAAQHER 360 VRHMYDWNDV AQRTVKVYDA VEASTRDDGL PARLRRYAAA GRWVGTFFGA VAVLSQLMMA 420 FLDWWQPRYL IDTAPDWPRS AGGDERERQG TWVQEADEQR EVAQPAATAP WVRTTPSRLA 480 GETGVLVSLY PMRSNKNIKN PTFMDAYAYN NIGRCV* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0438 | RfaG | 1.0e-36 | 11 | 381 | 390 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
| pfam08288 | PIGA | 5.0e-46 | 49 | 138 | 90 | + PIGA (GPI anchor biosynthesis). This domain is found on phosphatidylinositol n-acetylglucosaminyltransferase proteins. These proteins are involved in GPI anchor biosynthesis and are associated with disease the paroxysmal nocturnal haemoglobinuria. | ||
| cd03798 | GT1_wlbH_like | 5.0e-54 | 19 | 381 | 373 | + This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS. | ||
| cd03801 | GT1_YqgM_like | 3.0e-57 | 11 | 378 | 379 | + This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. | ||
| cd03796 | GT1_PIG-A_like | 0 | 11 | 408 | 400 | + This family is most closely related to the GT1 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0006506 | GPI anchor biosynthetic process |
| GO:0009058 | biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EFA80496.1 | 0 | 3 | 441 | 25 | 482 | GlcNAc transferase [Polysphondylium pallidum PN500] |
| RefSeq | XP_001700288.1 | 0 | 8 | 436 | 6 | 443 | glycosyl transferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001768792.1 | 0 | 14 | 438 | 1 | 421 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002279568.1 | 0 | 5 | 447 | 2 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002529442.1 | 0 | 6 | 454 | 2 | 444 | glycosyltransferase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2gek_A | 0.000000000001 | 11 | 384 | 22 | 386 | A Chain A, Crystal Structure Of The C-terminal Globular Domain Of Oligosaccharyltransferase (afaglb-s2, Af_0040, O30195_arcfu) From Archaeoglobus Fulgidus |
| PDB | 2gej_A | 0.000000000001 | 11 | 384 | 22 | 386 | A Chain A, Crystal Structure Of Phosphatidylinositol Mannosyltransferase (Pima) From Mycobacterium Smegmatis In Complex With Gdp-Man |
| PDB | 3mbo_H | 0.000000005 | 5 | 323 | 25 | 343 | A Chain A, Crystal Structure Of The Glycosyltransferase Babsha Bound With Udp And L-Malate |
| PDB | 3mbo_G | 0.000000005 | 5 | 323 | 25 | 343 | A Chain A, Crystal Structure Of The Glycosyltransferase Babsha Bound With Udp And L-Malate |
| PDB | 3mbo_F | 0.000000005 | 5 | 323 | 25 | 343 | A Chain A, Crystal Structure Of The Glycosyltransferase Babsha Bound With Udp And L-Malate |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EE592228 | 231 | 1 | 231 | 0 |
| EE592228 | 208 | 229 | 436 | 0 |
| DY295948 | 293 | 7 | 299 | 0 |
| DY942002 | 274 | 9 | 282 | 0 |
| BI719545 | 179 | 8 | 185 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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