| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20001869m |
| Family | GT47 |
| Protein Properties | Length: 937 Molecular Weight: 106896 Isoelectric Point: 8.4701 |
| Chromosome | Chromosome/Scaffold: 22 Start: 705767 End: 718388 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 546 | 860 | 8.2e-35 |
| VLRIYVYDLPANAAFMVALDDNVFDLNEPSYQTHRKFLELLLRDNAVRTENPLEANLFFVPANAYAYSSNTNPPTNQGVRVLPKWARLSSLSITLPNTIR TSTPVGVRTISFGPPLSNVIHVTLFGLHANLRDNTTTFLKPAPEHHPTWGCYHPKKDVLAAPWYDHMLGSKEAVHLYGSLSDAGGEAPNRDLLFFFAGSV RPRDTSYSGGARQALSAHLKALMASGGNYSDIQFVEGTVPDYEALYMRSRFCLAPHGAGFGVRLTLAMTHACIPVIIQDQVYQPYESDGLLPYSQFSLRL SKSDIPYIVDILRSV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 937 Download |
| MISPRRIGKL VAFFLSLNLL ALDSNALAHR DAKTARNASR RKELDLPRRL NGKRLLSMHG 60 DVGSLALTTA THPDVGLDHL FQPLKLDCHP DCVKRGNCNA EEGRCEWLLE PLGIAIRQDW 120 MKATCGPTCE EPLLSGCQRG PGLEPFFGVL VSRNCECLRQ ANRFFGCSPN NDTCTLASMS 180 FHDVQCYTFP DLPPEQQYSQ MPSLDQPGVQ YYRGSINRVV DLKPVGPAEG LVGRDIWSRG 240 GGKGSAVRGR FPVLALVLVS ACTTLRTFLP RHVVLRAYLG LPPEKCGTTK CHGRGACVLE 300 VQSTELDALR TATEGNYSPY CMCYKGYMGH HCKCGVYCVS GCRAYRQHVF RKGAQESGHY 360 PPTSTSTSTG RLPLISMLYS PVLHLQHNYY YYYYYYYYYY YYYYYYYYYY YYYYYYYYYY 420 YYYYYYYYYY YYYCYYYILL LLLLLLLLLL LEDMLELCPS NCRGRGRCIR GFCHCKYEKG 480 TYHQPPRHKH THTDTAFAGS SIPHTRCPFS LYPPGMTPPP YWGLDCSRER AWQLAPGAPH 540 IPNRHVLRIY VYDLPANAAF MVALDDNVFD LNEPSYQTHR KFLELLLRDN AVRTENPLEA 600 NLFFVPANAY AYSSNTNPPT NQGVRVLPKW ARLSSLSITL PNTIRTSTPV GVRTISFGPP 660 LSNVIHVTLF GLHANLRDNT TTFLKPAPEH HPTWGCYHPK KDVLAAPWYD HMLGSKEAVH 720 LYGSLSDAGG EAPNRDLLFF FAGSVRPRDT SYSGGARQAL SAHLKALMAS GGNYSDIQFV 780 EGTVPDYEAL YMRSRFCLAP HGAGFGVRLT LAMTHACIPV IIQDQVYQPY ESDGLLPYSQ 840 FSLRLSKSDI PYIVDILRSV STERQKRMRL AMAKYHHAFL WEPSLGGRAY NYTIRALNQR 900 LHGLWGHLWG DPHPAERRHL RVAWDDAQDE GELADM* 960 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-19 | 544 | 860 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693329.1 | 0 | 453 | 908 | 178 | 598 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693348.1 | 0 | 551 | 900 | 1 | 338 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694986.1 | 0.00000003 | 88 | 215 | 30 | 143 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694986.1 | 0 | 458 | 905 | 228 | 676 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694987.1 | 0 | 458 | 905 | 256 | 700 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
