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Basic Information | |
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Species | Volvox carteri |
Cazyme ID | Vocar20002407m |
Family | GT47 |
Protein Properties | Length: 657 Molecular Weight: 73627.5 Isoelectric Point: 7.3252 |
Chromosome | Chromosome/Scaffold: 2 Start: 2239331 End: 2246018 |
Description | exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 291 | 600 | 0 |
LKIYMYDIPPNIVGPHQFEDGNGGIHPQYESFLRFQGLFLNDVSGIRTENPHEANLFYIPAFTYYSSSNLGDPTGAAVRAVNWVAATFPFFNRTGGRDHF VLLSGDRGACYLKTLPQTENLIRVTHFGYERPNITDMGPLVTNTEYGCFKAGRDVVMPPYVKSNVAGIQGVRAKLEEPGGAEALLAGKDTLLFFSGDIRH NEPEYSGGVRQALALLLANTSYPDVVFKGGYMMMGMGEYESLLRRSKFCLAPYGHGWGIRLIHAITHACIPVIIQDKVRQPFEDILHYPDFSVRVSKAEL PRLVEILRAV |
Full Sequence |
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Protein Sequence Length: 657 Download |
MLQRLALVPL LTILLLHFVR RVQPAETVLK TALTDQPFNQ FQEVNKPCQD GCLEHGNCNR 60 ELGECECPFG LSGPTCQTQL YPACRTTPTT QRIFLGRMAP RNCYCYREVM KAMCLPEEET 120 RCATHTMQLW DALFCFEKVG VPEDQQISEL PEKMDDPSYR WGKGTTVREV VDGVPKLRRE 180 IQMLSQPPSV EDTSRTVPLS RCERRCSERG VCQDWGQQTI CLCFAGFRRP DCSQLVEEGA 240 EPACPNGCGG RGKCVAGFCK CEPPYWGIGC SRSTAYEPVP GSVAYPYFPS LKIYMYDIPP 300 NIVGPHQFED GNGGIHPQYE SFLRFQGLFL NDVSGIRTEN PHEANLFYIP AFTYYSSSNL 360 GDPTGAAVRA VNWVAATFPF FNRTGGRDHF VLLSGDRGAC YLKTLPQTEN LIRVTHFGYE 420 RPNITDMGPL VTNTEYGCFK AGRDVVMPPY VKSNVAGIQG VRAKLEEPGG AEALLAGKDT 480 LLFFSGDIRH NEPEYSGGVR QALALLLANT SYPDVVFKGG YMMMGMGEYE SLLRRSKFCL 540 APYGHGWGIR LIHAITHACI PVIIQDKVRQ PFEDILHYPD FSVRVSKAEL PRLVEILRAV 600 PEPDLLRMIK ENSRVYRAFL WQPELGGLAY NITIASLRRR LSHVRGDLYE AGVRRS* 660 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam07974 | EGF_2 | 0.005 | 50 | 76 | 27 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
pfam03016 | Exostosin | 2.0e-40 | 289 | 600 | 317 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001693329.1 | 0 | 67 | 649 | 2 | 599 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001693348.1 | 0 | 295 | 649 | 1 | 347 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001694986.1 | 0 | 28 | 640 | 10 | 671 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001694987.1 | 0 | 41 | 640 | 41 | 695 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001699926.1 | 0 | 41 | 641 | 167 | 774 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |