| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20003733m |
| Family | GT47 |
| Protein Properties | Length: 573 Molecular Weight: 64406.1 Isoelectric Point: 8.0966 |
| Chromosome | Chromosome/Scaffold: 33 Start: 260410 End: 266775 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 136 | 437 | 4.49999e-41 |
| KRGPKIYVYEIPPDFHVKRDIHKVDRPPLHMALMERILSGGHRTADPEKADFFYIPASARDLKRAFLLEPLLNYIIEAWPIWNQTGGARHIMPAEGDVGT CELPMKIRNMTANVTWLQFWGMYDFHPHWTQIFHNRVPCMVPGRDIVVPFMAMSSHDRFVIETPLHPRNQKRNRTNTFFFAGGICGSGNKRALPPHCTYY KQVRYSGGVRQAVYYHYHKRPGWRVVPGTDDYARDYASSIFCLAAAGGGWGKRGIVATMYGCIPVAATDMLYEAFEPEMDWNRFGVRVSQAQIPQLGDML EA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 573 Download |
| MRGALAWASV CILAVLCGTF LAPTAFGRKA CPEGCHKFGT CNEELGRCDC PWNYTGPSCT 60 IAYRGFCVKR VGVDNPINTC KDGDPTLCVN ACNGRGDCKG GFCHCKPGFF GVDCALSYNK 120 QGEAEVLAGM DYRLNKRGPK IYVYEIPPDF HVKRDIHKVD RPPLHMALME RILSGGHRTA 180 DPEKADFFYI PASARDLKRA FLLEPLLNYI IEAWPIWNQT GGARHIMPAE GDVGTCELPM 240 KIRNMTANVT WLQFWGMYDF HPHWTQIFHN RVPCMVPGRD IVVPFMAMSS HDRFVIETPL 300 HPRNQKRNRT NTFFFAGGIC GSGNKRALPP HCTYYKQVRY SGGVRQAVYY HYHKRPGWRV 360 VPGTDDYARD YASSIFCLAA AGGGWGKRGI VATMYGCIPV AATDMLYEAF EPEMDWNRFG 420 VRVSQAQIPQ LGDMLEAFTP EQIRQMQIRT ACAAQHLHWS TNLGGIMGET GEFDAFNTIM 480 AILRMRRKRP DLLPQQYYEE DEEFRNFIDC KPFRPTAQHI PLCTMYTGPG MELRGFEDSC 540 PAAVYYFRRK LGPPGGAICA LSQDTASCPL FD* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.001 | 32 | 59 | 28 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 2.0e-35 | 136 | 438 | 322 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693540.1 | 0 | 31 | 501 | 5 | 487 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699869.1 | 0 | 27 | 470 | 28 | 427 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702517.1 | 0 | 33 | 485 | 13 | 479 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 29 | 511 | 71 | 554 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 40 | 511 | 3 | 472 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
