| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20003855m |
| Family | GT28 |
| Protein Properties | Length: 373 Molecular Weight: 38636.8 Isoelectric Point: 10.2318 |
| Chromosome | Chromosome/Scaffold: 37 Start: 249369 End: 255471 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT28 | 198 | 341 | 1.3e-39 |
| LLVLGGSGGCGYLNCAVNNALPQLAGVPGLHVLWQTGAKQYVSYSAGYAASLPSVRCVPFLPEPGSALLAADLVLSRAGASTVSELGAVGVPALLVPSPA VSNEQQTANARVLVDKNQAVLVPQVEVDEGGLAPHLLPLLTPTD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 373 Download |
| MSTNFRRTAL GACTTVAAVY AAAFTAVRAV FLGESRGPEL HVVPQCGFKL YCISSVSLQR 60 PLKSVSNALN IFRFPLCVAH SAWALVRAGP HVLVGTGGKV SVPACVAAAA LGIPLVLYEP 120 NAQAGAANQA LHVIARQTLL AYDSAAAGLR YKDRCVVVGP AVRSDVLDCV WGGQGAVRRR 180 RRKARAALGV TGRGTRLLLV LGGSGGCGYL NCAVNNALPQ LAGVPGLHVL WQTGAKQYVS 240 YSAGYAASLP SVRCVPFLPE PGSALLAADL VLSRAGASTV SELGAVGVPA LLVPSPAVSN 300 EQQTANARVL VDKNQAVLVP QVEVDEGGLA PHLLPLLTPT DGRRLAGMRR GSCVDLSSQQ 360 KTTGRHNTCN KR* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04101 | Glyco_tran_28_C | 1.0e-19 | 211 | 330 | 121 | + Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site. | ||
| TIGR01133 | murG | 5.0e-36 | 31 | 323 | 298 | + undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]. | ||
| COG0707 | MurG | 4.0e-38 | 31 | 323 | 300 | + UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] | ||
| PRK00726 | murG | 2.0e-53 | 31 | 330 | 318 | + undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional | ||
| cd03785 | GT1_MurG | 8.0e-59 | 31 | 330 | 318 | + MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030246 | carbohydrate binding |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001696869.1 | 0 | 24 | 367 | 58 | 435 | hypothetical protein CHLREDRAFT_192581 [Chlamydomonas reinhardtii] |
| RefSeq | YP_003239509.1 | 6.99949e-42 | 24 | 350 | 25 | 346 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Ammonifex degensii KC4] |
| RefSeq | YP_360888.1 | 2e-38 | 30 | 364 | 34 | 357 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Carboxydothermus hydrogenoformans Z-2901] |
| RefSeq | YP_592704.1 | 7.00005e-41 | 30 | 337 | 33 | 319 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Candidatus Koribacter versatilis Ellin345] |
| RefSeq | ZP_03390483.1 | 4e-38 | 30 | 325 | 35 | 315 | undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase [Capnocytophaga sputigena Capno] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3s2u_A | 3e-27 | 31 | 350 | 35 | 336 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_B | 4e-23 | 31 | 325 | 39 | 313 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_A | 4e-23 | 31 | 325 | 39 | 313 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1f0k_B | 4e-23 | 31 | 325 | 39 | 313 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| PDB | 1f0k_A | 4e-23 | 31 | 325 | 39 | 313 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
