| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20005376m |
| Family | GT47 |
| Protein Properties | Length: 555 Molecular Weight: 62026.8 Isoelectric Point: 9.0292 |
| Chromosome | Chromosome/Scaffold: 123 Start: 16682 End: 20526 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 116 | 387 | 2.8e-38 |
| EKRPWVYVYELPPHLFTWLNTKRLDRSTHLMFYQRLLGSGARVADGDLADWYYIPIRLRTATDSAFLKYAIEYIREAYPWWNRTGGARHFVIHTGDLGAD EVMDDVYGMAANMTWLTHWGLTVDKNTSGWWKAHRPDKARAGARWGTRGGYYTRVSVNRRRGSHMWGPPSPAPHRAGVRQKVHFHHWNRTGFRIVTFERN YGKALVSSKFCLAPLGGGHGQRQIIVSYMGCIPVCIADGVYEPFEPQTDWTEFAVRPAEADIPRLHEILEGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 555 Download |
| MLRCYQRLYR PLHLQFYSQL FLSKSCDCPK NRTGPSCLDV ADRSILRGRC AKAFYPSIME 60 CTKSELSCLN NCNKKGTCTG GWCHCQPGRF GADCSLSLGP DGRPQLLADK GYQTREKRPW 120 VYVYELPPHL FTWLNTKRLD RSTHLMFYQR LLGSGARVAD GDLADWYYIP IRLRTATDSA 180 FLKYAIEYIR EAYPWWNRTG GARHFVIHTG DLGADEVMDD VYGMAANMTW LTHWGLTVDK 240 NTSGWWKAHR PDKARAGARW GTRGGYYTRV SVNRRRGSHM WGPPSPAPHR AGVRQKVHFH 300 HWNRTGFRIV TFERNYGKAL VSSKFCLAPL GGGHGQRQII VSYMGCIPVC IADGVYEPFE 360 PQTDWTEFAV RPAEADIPRL HEILEGISAG NKLAEMQVAL RCAAQHLLYS SMVGGLFGED 420 GRYDAFETTL EVLRVKAAHP DAPPESYRKL DPDFDTFMRC RDPPGWKVSG PVPDMWGMLD 480 GGGGGESGLG AGVGGKGGAV AEQQNPLCSH SIMDRGRLPC ERFVQGSSKT HGIPGGIICA 540 RSRHNLAKCP RTWL* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-31 | 115 | 387 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693540.1 | 0 | 26 | 460 | 22 | 496 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693783.1 | 0 | 26 | 553 | 59 | 610 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 26 | 473 | 90 | 560 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 26 | 466 | 10 | 477 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703125.1 | 0 | 25 | 474 | 83 | 526 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| BU654073 | 227 | 27 | 250 | 0 |
| AV627636 | 160 | 57 | 213 | 7.00649e-44 |
| BI532593 | 157 | 317 | 472 | 8e-37 |
| FD821819 | 224 | 336 | 553 | 5e-36 |
| BI532624 | 151 | 323 | 472 | 3e-34 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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