| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20005616m |
| Family | GT47 |
| Protein Properties | Length: 516 Molecular Weight: 57943.3 Isoelectric Point: 7.283 |
| Chromosome | Chromosome/Scaffold: 11 Start: 1438335 End: 1448290 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 159 | 314 | 1.5e-25 |
| RRPLIYVYDTDPIFNTKMIQYRLARTSCVYRLFGAGNDTFYNNFVYTLESYWIEMLTISQHRTFDPEEADFFFVPVQLTCYLWPVLGWADHPWFGMPAAH SRAHQGASMYLSAKRWIQQHYPYWDRRGGRDHIWMMLNDEGACWMPTEVYNTSIIL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 516 Download |
| PPGTKYGRTL APPDAPPGTP PLQAGRPMGD SCKPGRDPAT GKRLDWGRLE PDDLFGPDGW 60 CNSENPRTHC GCLLDGSQGH FCDTPTEAFC FNQCSGHGEC KLGFCKCHEG WYGMDCSRLR 120 ASAKEVTKGD HEGGSKSYLQ GIVVNPPAAQ DPPPVPTRRR PLIYVYDTDP IFNTKMIQYR 180 LARTSCVYRL FGAGNDTFYN NFVYTLESYW IEMLTISQHR TFDPEEADFF FVPVQLTCYL 240 WPVLGWADHP WFGMPAAHSR AHQGASMYLS AKRWIQQHYP YWDRRGGRDH IWMMLNDEGA 300 CWMPTEVYNT SIILSHWGRM DEAHVSGTAW GYDNYTSPLE SWPPYFDGDW RTIIEGHPCY 360 TPGKAGPQAR LGHPISGSYS EHLARSKFCV FLLHISPEQV ERMQRRLAVV WHRFAYAAGP 420 LLSGALQRAY ESNRHRRMQA VTDEEGQAKE ALERMSKEVT GSTMAAGGGG PGVNAGEWLG 480 PPGHPFTALT RFPVRSDAWN TIMAWLHSRI PFTRG* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-13 | 158 | 306 | 149 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001691329.1 | 0 | 5 | 411 | 199 | 624 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001691329.1 | 0.000002 | 392 | 514 | 717 | 815 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001696764.1 | 0 | 1 | 364 | 270 | 632 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001696764.1 | 0.00000000004 | 391 | 467 | 779 | 855 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001696822.1 | 0 | 1 | 305 | 961 | 1267 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD884517 | 254 | 1 | 254 | 0 |
| FD867786 | 115 | 260 | 374 | 0 |
| BI717917 | 202 | 158 | 359 | 0 |
| BI718248 | 209 | 157 | 360 | 0 |
| FD801053 | 262 | 103 | 364 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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