Basic Information | |
---|---|
Species | Volvox carteri |
Cazyme ID | Vocar20005743m |
Family | GT47 |
Protein Properties | Length: 504 Molecular Weight: 57903 Isoelectric Point: 5.7153 |
Chromosome | Chromosome/Scaffold: 11 Start: 1073442 End: 1081556 |
Description | exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 298 | 494 | 1.6e-25 |
EFKIYMYELPWEIAFPYELGEDVHTRDNIYTAYEEFMKYFLVDDMVRTQNPYEANLFYVPALTYFYATNVRNGQWQAEAVIEYIRTKWPFYNRTGGRDHF VFFTGDRASCHFQRWIQDSVIKVVHFGMQHRNLTWNEISNRDYACIQNKRDLVVPPRTVNLGPLLPSFSTPYYKWLVSNQGYDGNRTLLFFFAGGVA |
Full Sequence |
---|
Protein Sequence Length: 504 Download |
MRCTLGGLRV SLLFLTNFLI IRGQNDLGNP VIPVLKGCPD GCGQRGNCNY EEGRCECPWG 60 YAGEFSPSCE VDRMAVCRQT PDDPGSCGFI MPKNCECYRE CYRLYCSKYG PDTNKCTNQW 120 WGAELFDATC WLYGSEERGP STDRPQNSSW YPEDPERETV WFARIPEMAG QSDYSDPELR 180 LKDEQRRFKS PWDRPWLVWH RAPNTAQPLS RCPNNCSNGR GVCIQREDAT QPECMCHYGF 240 TESDCGAPCW FSPNCGGRGR CQSGFCKCDD GAWGVGCHRT AAFQPATPGA VPDLRSTEFK 300 IYMYELPWEI AFPYELGEDV HTRDNIYTAY EEFMKYFLVD DMVRTQNPYE ANLFYVPALT 360 YFYATNVRNG QWQAEAVIEY IRTKWPFYNR TGGRDHFVFF TGDRASCHFQ RWIQDSVIKV 420 VHFGMQHRNL TWNEISNRDY ACIQNKRDLV VPPRTVNLGP LLPSFSTPYY KWLVSNQGYD 480 GNRTLLFFFA GGVADGEYSG GVRL |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-18 | 299 | 503 | 214 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001693329.1 | 0 | 57 | 503 | 2 | 447 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001693348.1 | 0 | 303 | 503 | 1 | 202 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001693349.1 | 0 | 31 | 170 | 43 | 193 | hypothetical protein CHLREDRAFT_205511 [Chlamydomonas reinhardtii] |
RefSeq | XP_001694919.1 | 0 | 36 | 428 | 11 | 387 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001694986.1 | 2e-40 | 29 | 428 | 21 | 404 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |