| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20008669m |
| Family | GT47 |
| Protein Properties | Length: 786 Molecular Weight: 89986.2 Isoelectric Point: 7.0882 |
| Chromosome | Chromosome/Scaffold: 1 Start: 8773234 End: 8786758 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 339 | 697 | 0 |
| RPLIYVYDMPPAYHSRMLQYRIGSDACMWRRFSEANDTYLLSMTYSVEVYLHEMMLQSEHRTFDPEEADFFYVPMYITCFMWPVMGWADFPWWHAPLAHT RPMHVSNMILEAYEWLSTTFPWWNRRGGRDHIWLMAPDEGACYMPTVVYNSSIILTHWGRMDPDHKSGSAFDQDIYDKDLPVAQFKGWRGLDWMEKSRPH LCYNPEKDLVIPAFKSPDHFQESPLLGAPPLERDILLYFRGDVGEGRRDHYSRGIRQKLFQFAHWGKWAEKYKIYIGTGETIGGSYSEHLARSKFCLVAP GDGWSARAEDAILHGCVPLVVMDGVHAVFESILDWDSFSIRIREDNQALQAIPELLTAI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 786 Download |
| MDLVAGGIRR GLWGAQLQVS HRRQQLGFQL PKVKHDISDK VYIANRVSTE DDGHALRQRC 60 ALARGTWCGQ YLQQQPLVPR PAPRGGKECP NACSGWGNCN YDTGICECPA GRTGADCGQE 120 LKRPCSNRYR HPHEFNVTTA VGHLGGDNHD LNPQEPGWLA SRCYGQQCAL LLTGIEQPRS 180 GLSGYCLDDI AMCTCGLDSK YRHWGRPMTD SCMIGHDKDG AVLEWGRPYI KYDDVYGPNG 240 WCNSPKPVLN CGCAWDGNAW PCDGSRRFEP FCVNQCTGHG DCYMGFCRCH PGWYGQDCSR 300 KKAGMELDEG YLSQRPWLRG TVVVPPASLP EPQMPTQMRP LIYVYDMPPA YHSRMLQYRI 360 GSDACMWRRF SEANDTYLLS MTYSVEVYLH EMMLQSEHRT FDPEEADFFY VPMYITCFMW 420 PVMGWADFPW WHAPLAHTRP MHVSNMILEA YEWLSTTFPW WNRRGGRDHI WLMAPDEGAC 480 YMPTVVYNSS IILTHWGRMD PDHKSGSAFD QDIYDKDLPV AQFKGWRGLD WMEKSRPHLC 540 YNPEKDLVIP AFKSPDHFQE SPLLGAPPLE RDILLYFRGD VGEGRRDHYS RGIRQKLFQF 600 AHWGKWAEKY KIYIGTGETI GGSYSEHLAR SKFCLVAPGD GWSARAEDAI LHGCVPLVVM 660 DGVHAVFESI LDWDSFSIRI REDNQALQAI PELLTAISPE RLAKMQRNLA RVWHRFAYAT 720 GPVMRSHYRA SSENIVRNYP REILEASYKL SQRDSPLRPV TDFPFQEDAF STIMQWLYHR 780 IDKTR* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.003 | 90 | 117 | 28 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 9.0e-49 | 339 | 697 | 360 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001691329.1 | 0 | 46 | 785 | 70 | 815 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001697121.1 | 0 | 25 | 785 | 46 | 801 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698039.1 | 0 | 9 | 785 | 54 | 809 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698117.1 | 0 | 2 | 785 | 17 | 800 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698801.1 | 0 | 60 | 785 | 133 | 942 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD867786 | 238 | 444 | 681 | 0 |
| BI717917 | 216 | 325 | 540 | 0 |
| BI718248 | 217 | 325 | 541 | 0 |
| FD801053 | 293 | 285 | 576 | 0 |
| DC848405 | 231 | 300 | 500 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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