| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20009656m |
| Family | GT47 |
| Protein Properties | Length: 1247 Molecular Weight: 136992 Isoelectric Point: 7.6879 |
| Chromosome | Chromosome/Scaffold: 1 Start: 7129286 End: 7141902 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 643 | 892 | 8.8e-24 |
| RGPRVYVYDLPPSMTTWRNDMRLDRPTLRLFQERITATGVRVGDGDTADWYFIPVVLRHFCDATTLSAAVSYIREMHPWWNRTQGHRHFVIATGDMGRSE SERGHLTANVTFVSYWGLHAPKLSSGWRASHRNATDIVLPVFLGSPKLSRMGIFTSRLHPKFATKAPHELRERNGPIFFFAGRICGDHSKPQVDGVWPNC KSPHNMGYSGGTRQKIHFHHWNRTGYFIQLGDRHYAKHLLTSKFCFGPTG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1247 Download |
| MIRRCDCPRH RAGLACEEEL DAKALSKRCL KLGYPDVQNC LSGDNRCLNG CNSRGACLAG 60 FCHCQKGFFG ADCALSLGAD GKPQVLADRG YRARSRGPRV YVYDLLPSMT TWLNDMRLDR 120 PTMRLFQERV TATGVRVGDG DTADWYFIPV TLRHTADAYT LSAAVSYIRE MHPWWNRTHG 180 HRHFVIAIGD MGRLESERGR QSTNVTFVTH WGLHAPKLFS GWKASHRNAT DIVLPVHFHH 240 WNRTGYFIQL GDRHYAKHLL TSKYCFGPTG GGHASTAMFA LKGQHHLPTT ECFRMSPSSH 300 LGERVRDAYV SAPFPPSLPS PPSLPPPPLP PLPPPPPPAF PPSPPPLPSI SLSHFPRMQA 360 VQAGCVPVVI SDDVLEAFEP FLDWNTFGVR LAEADIPRMH EVLEAISPEE YAHKEVLLRC 420 AAQHMAFSTV TGSYIGESGR YDAFETLLEI LRAKAAHPDT PPEQLRQVDP QLDAFLDCRD 480 PNDPDMAPAP ATDGGAAAGG AEAGGGGGGG EVDGTTRGDG GSDGGSEQRL QESSSSADSD 540 RGSSRSRLSV VPTSSMISNM RLCSVSPFDA GDSDTPSCKS LRTQRRGALY VFINCQKPDD 600 GYRAFMQAQR RWDGFFGADC ALSLGADGKP QVLADRGYRA RSRGPRVYVY DLPPSMTTWR 660 NDMRLDRPTL RLFQERITAT GVRVGDGDTA DWYFIPVVLR HFCDATTLSA AVSYIREMHP 720 WWNRTQGHRH FVIATGDMGR SESERGHLTA NVTFVSYWGL HAPKLSSGWR ASHRNATDIV 780 LPVFLGSPKL SRMGIFTSRL HPKFATKAPH ELRERNGPIF FFAGRICGDH SKPQVDGVWP 840 NCKSPHNMGY SGGTRQKIHF HHWNRTGYFI QLGDRHYAKH LLTSKFCFGP TGGGHVVAAL 900 YGFVTNPRTP GKSKCRSSLA VLNQHHRGSA HHHDCCSEFA TIIRSCGPTA LSQRPSMSCT 960 PAIYLATLLT CLHVPMPPLL PSPSPSPLPR RLMQAVQAGC VPVVISDDVL EAFEPFLDWN 1020 TFGVRLAEAD IPRMHEVLEA ISPEEYARKE VLLRCAAQHM AFSTVTGSYI GESGRYDAFE 1080 TLLEILRAKA AHPDTPPEQL RQVDPQLDAF LDCRDPNDPD MAAAPALAAA DGGAVDGKMD 1140 RSSLPSDQHQ QQQGQRQQPG LELPSISDSD SDSSSRILSS SRSSSSSSGG RNTEEERLCS 1200 VSLLDEDDPA GHSCRSISAR RMETLFGGYM CIRKPLDPAA CPRPWL* 1260 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-10 | 994 | 1041 | 48 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 5.0e-10 | 358 | 406 | 49 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 9.0e-12 | 641 | 894 | 271 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 6.0e-12 | 94 | 240 | 160 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693783.1 | 0 | 4 | 257 | 58 | 319 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693783.1 | 0 | 614 | 904 | 123 | 422 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 4 | 481 | 9 | 474 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 569 | 895 | 23 | 346 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 6e-39 | 999 | 1116 | 357 | 474 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| BU654073 | 227 | 6 | 227 | 1.4013e-45 |
| AV627636 | 149 | 47 | 193 | 6.00036e-42 |
| BU654073 | 166 | 614 | 774 | 2e-36 |
| AV627636 | 129 | 614 | 740 | 1e-32 |
| BI722824 | 167 | 4 | 168 | 1e-29 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
