| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20009740m |
| Family | GT47 |
| Protein Properties | Length: 581 Molecular Weight: 63377.9 Isoelectric Point: 7.9871 |
| Chromosome | Chromosome/Scaffold: 1 Start: 7879371 End: 7884638 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 11 | 288 | 1.49939e-42 |
| HVYFWQRLLGSGARVADGDLADWYFIPVRQRSFSDSWFLREALSYIRTHHPWWNRTEGHRHMVLHTGDWGLGEVAKDVRQMSLNVTWLTHWGLSTDRPNI QRWTRAFRPERDVVIPVYISPGHFVHFGINRSPLHPVTAASRRTAARPRNESLLFFAGRICHDAKRPNPDTFPACGDDTAEWYGGGVREKFFVSHWNRSG FHVVRSEPRYSHYMSRSVFCLAPPGAGHGQRQIQALFMGCVPVTVADGVYEPFEPALSWEEWGLRIAEQDIPRAHELL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 581 Download |
| SNLRRLDRPL HVYFWQRLLG SGARVADGDL ADWYFIPVRQ RSFSDSWFLR EALSYIRTHH 60 PWWNRTEGHR HMVLHTGDWG LGEVAKDVRQ MSLNVTWLTH WGLSTDRPNI QRWTRAFRPE 120 RDVVIPVYIS PGHFVHFGIN RSPLHPVTAA SRRTAARPRN ESLLFFAGRI CHDAKRPNPD 180 TFPACGDDTA EWYGGGVREK FFVSHWNRSG FHVVRSEPRY SHYMSRSVFC LAPPGAGHGQ 240 RQIQALFMGC VPVTVADGVY EPFEPALSWE EWGLRIAEQD IPRAHELLGG LTREQLAEKQ 300 SRMHCAAQHM LYSTITGAVL GEDGRYDAFE TTLEVLRVRA AHPDAPQQDF RRLDPDFAAF 360 MDCRPPPGFK WLDGKVERRT PTSTGGTTDT KAGKPTDSSG ARARSSQGQD QDQAALAIAA 420 AAVGQSVVSA TGGEVGSGFG FHSAALGDAQ SEGNSSLYGA ERVVVGDGEG EGEEGALATV 480 GGDDAGGAGR GDIVNVGVVN GTGTSGSSFF QNSSSSYTLP PPPGTGLVPG LCSHAARDLR 540 FRERSCYQVL RGGGYMGVPG GAMCAKGFKT RLAACPRLWG * 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-30 | 12 | 288 | 291 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693540.1 | 0 | 2 | 363 | 136 | 496 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693783.1 | 0 | 6 | 353 | 176 | 521 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 2 | 363 | 195 | 553 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 1 | 373 | 118 | 481 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703125.1 | 0 | 2 | 368 | 195 | 512 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD838948 | 283 | 61 | 333 | 1.4013e-45 |
| BI532593 | 156 | 211 | 365 | 5.99994e-41 |
| BI532624 | 161 | 206 | 365 | 5e-38 |
| BU654073 | 119 | 2 | 118 | 9e-29 |
| HO423892 | 338 | 13 | 341 | 1e-28 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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